Evidence supporting the use of: Laxogenin
For the health condition: Athletic and Exercise Aids
Synopsis
Source of validity: Scientific
Rating (out of 5): 1
Laxogenin is a plant-derived steroidal sapogenin, often marketed as a "natural anabolic" compound in the sports supplement industry. It is claimed to support muscle growth, strength, and athletic recovery. However, the evidence supporting these claims is extremely limited. There are no published human clinical trials directly evaluating laxogenin’s effects on muscle mass, performance, or recovery. Most of the purported benefits are extrapolated from in vitro or animal research, which suggests that similar brassinosteroids (a class of plant hormones) may have anabolic effects in non-human models. Nevertheless, laxogenin itself has not been adequately studied in humans for athletic or exercise-related purposes.
The ingredient’s popularity is largely driven by marketing and anecdotal reports within the fitness community, rather than robust scientific validation. Regulatory bodies, including the FDA, have issued warnings about the inclusion of laxogenin in dietary supplements due to a lack of safety and efficacy data. In summary, while laxogenin is used as an athletic and exercise aid, current scientific evidence supporting its effectiveness is minimal, and its safety profile in humans remains unclear.
Other ingredients used for Athletic and Exercise Aids
1,3,7-Trimethylpurine-2,6-dione7-Keto-DHEA
Acetyl L-carnitine
Acetyl-L-Tyrosine
adenosine 5-triphosphate disodium (ATP)
Adenosine triphosphate (ATP)
Agmatine
Algae
Algal protein
Alpha D-ribofuranose
Alpha glyceryl
Alpha hydroxyisocaproic acid
alpha-ketoglutarate (AKG)
Alpha-ketoisocaproic acid
amino acids
antler
arachidonic acid
arginine alpha ketoglutarate
Arginine aspartate
arginine creatine
Arginine malate
Arginine nitrate
Arginine silicate
ashwagandha
astaxanthin
ba ji tian
bacillus subtilis
BCAA
bee pollen
Beef Protein
beet
beta-alanine
bicarbonate
black ginger
black tea
bovine
bovine protein
branched-chain amino acids
brown rice protein
Bulbine natalensis
caffeine
Camellia sinensis
capsaicinoids
capsiate
capsicum
capsinoids
cardarine
casein
cistanche
citrate malate
cocoa
coconut
coenzyme Q10 (CoQ10)
collagen
colostrum
conjugated linoleic acid (CLA)
cordyceps
creatine
creatine monohydrate
curcumin
D-Aspartic Acid
D-Ribose
deer velvet
dihydrocapsiate
ecdysteroids
ecdysterone
electrolytes blend (proprietary)
eleuthero
elk antler
Ephedra
ephedrine
Ethyl-Alpha-Guanido-Methyl-Ethanoate
Eurycoma Longifolia
eurycomanone
Fadogia agrestis
ginseng
Ginsenosides
glucose
Glutamine
Glycerol
Glycocyamine
GMS-ribose
green tea
guanidinoacetic acid
guarana
Guaranine
guayusa
Higenamine
HMB hydroxymethylbutyrate
horny goat weed
hydroxymethylbutyrate
Isoleucine
isomaltulose
jiaogulan
ketone salts
kola nut
L-alanine
L-alanyl-L-glutamine
L-arginine
l-carnitine
L-citrulline
L-glutamine
L-glycine
l-isoleucine
L-leucine
L-ornithine
L-taurine
l-tyrosine
L-valine
lactalbumin
Laxogenin
maca
macaenes
macamides
magnesium
maral root
Mate
Methylliberine
Methylxanthine
Milk Protein
Mineral ascorbate
Muira puama
Mushroom
Nitrous Malate (TM) Diarginine Malate
omega-3 fatty acids
Ornithine
ornithine alpha-ketoglutarate
Palatinose
paraxanthine
Peppermint
Peptides
Phosphatidic Acid
Phosphocreatine
Phytoecdysteroid
Piper nigrum
protein
pyridoxal-5-phosphate (P-5-P)
pyrroloquinoline quinone
pyruvate
Quinoa Protein
Rhaponticum
Rhodiola
ribose
robusta coffee
Safed musli
salt
sea salt
Sida cordifolia
spirulina
suma
Synephrine
Teacrine
Theacrine
Theobromine
Tongkat ali
tribulus
Tribulus Terrestris
Trichilia catigua
Trichopus zeylanicus
Turkesterone
Valine alpha-hydroxyisocaproate
vitamin C
Watermelon
Whey protein
Xanthine
Yerba mate
Yohimbine