Evidence supporting the use of: Laxogenin
For the health condition: Athletic and Exercise Aids
Synopsis
Source of validity: Scientific
Rating (out of 5): 1
Laxogenin is a plant-derived steroidal sapogenin, often marketed as a "natural anabolic" compound in the sports supplement industry. It is claimed to support muscle growth, strength, and athletic recovery. However, the evidence supporting these claims is extremely limited. There are no published human clinical trials directly evaluating laxogenin’s effects on muscle mass, performance, or recovery. Most of the purported benefits are extrapolated from in vitro or animal research, which suggests that similar brassinosteroids (a class of plant hormones) may have anabolic effects in non-human models. Nevertheless, laxogenin itself has not been adequately studied in humans for athletic or exercise-related purposes.
The ingredient’s popularity is largely driven by marketing and anecdotal reports within the fitness community, rather than robust scientific validation. Regulatory bodies, including the FDA, have issued warnings about the inclusion of laxogenin in dietary supplements due to a lack of safety and efficacy data. In summary, while laxogenin is used as an athletic and exercise aid, current scientific evidence supporting its effectiveness is minimal, and its safety profile in humans remains unclear.
Other ingredients used for Athletic and Exercise Aids
7-Keto-DHEAAcetyl L-carnitine
adenosine 5-triphosphate disodium (ATP)
Alpha D-ribofuranose
alpha-ketoglutarate (AKG)
amino acids
ashwagandha
astaxanthin
bacillus subtilis
beet
beta-alanine
black tea
bovine
branched-chain amino acids
caffeine
capsaicinoids
coenzyme Q10 (CoQ10)
collagen
colostrum
conjugated linoleic acid (CLA)
cordyceps
creatine monohydrate
curcumin
eleuthero
ginseng
green tea
guarana
guayusa
l-isoleucine
L-alanine
L-Alanyl-L-glutamine
L-arginine
l-carnitine
L-citrulline
L-glutamine
L-glycine
L-leucine
L-Ornithine
L-taurine
l-tyrosine
L-valine
maca
magnesium
maltodextrin
muira puama
Acetyl-L-Tyrosine
omega-3 fatty acids
ornithine alpha-ketoglutarate
Peppermint
protein
pyridoxal-5-phosphate (P-5-P)
rhodiola
black ginger
spirulina
tongkat ali
tribulus
vitamin C
watermelon
whey protein
suma
jiaogulan
capsicum
bee pollen
cistanche
electrolytes blend (proprietary)
yerba mate
Algae
cocoa
brown rice protein
sea salt
1,3,7-Trimethylpurine-2,6-dione
Arginine Alpha Ketoglutarate
Antler
Arginine Creatine
Arginine nitrate
Arachidonic Acid
Arginine malate
Arginine aspartate
Alpha glyceryl
Alpha-ketoisocaproic acid
Agmatine
Adenosine triphosphate (ATP)
Algal protein
Alpha hydroxyisocaproic acid
Arginine silicate
Bicarbonate
Beef Protein
Bovine Protein
Bulbine natalensis
Ba Ji Tian
BCAA
Camellia sinensis
Coconut
Casein
Cardarine
Capsinoids
Citrate malate
Capsiate
Creatine
D-Aspartic Acid
Dihydrocapsiate
Deer Velvet
D-Ribose
Ephedra
Eurycomanone
Elk antler
Eurycoma Longifolia
Ecdysteroids
Elthyl-Alpha-Guanido-Methyl-Ethanoate
Ecdysterone
Ephedrine
Fadogia agrestis
Guanidinoacetic acid
Ginsenosides
Glutamine
Growth factors
GMS-ribose
glucose
Glycocyamine
Guaranine
Glycerol
Higenamine
Hydroxymethylbutyrate
HMB Hydroxymethylbutyrate
Horny Goat Weed
Isomaltulose
Isoleucine
Kola Nut
Ketone Salts
Lactalbumin
Laxogenin
Macamides
Maral Root
Mineral ascorbate
Milk Protein
Methylxanthine
Methylliberine
Mate
Mushroom
Macaenes
Nitrous Malate (TM) Diarginine Malate
Ornithine
Phosphocreatine
Pyrroloquinoline Quinone
Paraxanthine
Phytoecdysteroid
Pyruvate
Phosphatidic Acid
Piper nigrum
Palatinose
Peptides
Quinoa Protein
Rhaponticum
Ribose
Robusta Coffee
Synephrine
Safed musli
salt
Sida cordifolia
Theobromine
Tripeptide
Trichilia catigua
Turkesterone
Trichopus zeylanicus
Theacrine
Teacrine
Tribulus Terrestris
Valine alpha-hydroxyisocaproate
Xanthine
yohimbine