Evidence supporting the use of: Ligandrol
For the health condition: Athletic and Exercise Aids
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Ligandrol (LGD-4033) is a selective androgen receptor modulator (SARM) that has garnered attention in the context of athletic and exercise aids due to its anabolic properties. Scientific interest in Ligandrol primarily stems from its potential to increase lean muscle mass and strength without many of the side effects associated with traditional anabolic steroids. Several early-phase clinical trials have demonstrated that Ligandrol can significantly increase lean body mass in healthy men and elderly individuals, with one notable study published in "The Journal of Clinical Endocrinology & Metabolism" (2013) showing dose-dependent increases in lean mass over a 21-day period. However, improvements in functional performance, such as strength or endurance, were less consistently observed or reported.
Despite these promising anabolic effects, Ligandrol has not been approved for medical use by regulatory agencies, and research on its long-term safety, efficacy, and potential for abuse remains limited. Furthermore, its use is prohibited in competitive sports by the World Anti-Doping Agency (WADA) due to its performance-enhancing potential. Most available evidence comes from small-scale, short-term human studies and preclinical research, so while there is scientific validation for its muscle-building effects, the evidence supporting its use specifically as an exercise aid or athletic performance enhancer is moderate and not yet conclusive. The risk of adverse effects and lack of regulatory approval further limit its recommended use outside of clinical research settings.
Other ingredients used for Athletic and Exercise Aids
7-Keto-DHEAacetyl l-carnitine
adenosine 5-triphosphate disodium (ATP)
alpha d-ribofuranose
alpha-ketoglutarate (AKG)
amino acids
ashwagandha
astaxanthin
bacillus subtilis
beet
beta-alanine
black tea
bovine
branched-chain amino acids
caffeine
capsaicinoids
coenzyme Q10 (CoQ10)
collagen
colostrum
conjugated linoleic acid (CLA)
cordyceps
creatine monohydrate
curcumin
eleuthero
ginseng
green tea
guarana
guayusa
l-isoleucine
l-alanine
l-alanyl-l-glutamine
l-arginine
l-carnitine
l-citrulline
l-glutamine
l-glycine
l-leucine
l-ornithine
l-taurine
l-tyrosine
l-valine
maca
magnesium
maltodextrin
muira puama
Acetyl-L-Tyrosine
omega-3 fatty acids
ornithine alpha-ketoglutarate
peppermint oil
protein
pyridoxal-5-phosphate (P-5-P)
rhodiola
black ginger
spirulina
tongkat ali
tribulus
vitamin C
watermelon
whey protein
suma
jiaogulan
capsicum
bee pollen
cistanche
electrolytes blend (proprietary)
yerba mate
algae
cocoa
brown rice protein
sea salt
1,3,7-Trimethylpurine-2,6-dione
2, 17a-dimethyl-17b-hydroxy-5a-androst-2-ene
Arginine Alpha Ketoglutarate
Antler
Arginine Creatine
Arginine nitrate
Arachidonic Acid
Arginine malate
Arginine aspartate
Alpha glyceryl
Alpha-ketoisocaproic acid
Agmatine
adenosine triphosphate (ATP)
Algal protein
Alpha hydroxyisocaproic acid
Arginine silicate
Bicarbonate
Beef Protein
Bovine Protein
Bulbine natalensis
Ba Ji Tian
BCAA
Camellia sinensis
Coconut
Casein
Cardarine
Capsinoids
Citrate malate
Capsiate
Creatine
D-Aspartic Acid
Dihydrocapsiate
Deer Velvet
D-Ribose
Ephedra
Elk antler
Ecdysteroids
Elthyl-Alpha-Guanido-Methyl-Ethanoate
Ecdysterone
Ephedrine
glucose
Isoleucine
Ketone Salts
Milk Protein
Quinoa Protein
salt
yohimbine
Other health conditions supported by Ligandrol
Athletic and Exercise AidsBody Building
Broken Bones
Cancer Treatment (reducing side effects)
Convalescence
Exercise
Muscle Tone (lack of)
Muscular Dystrophy
Osteoporosis
Wasting