Evidence supporting the use of: Active Amines
For the health condition: Attention Deficit Disorder

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Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Active amines, particularly amphetamine and methylphenidate derivatives, are well-established pharmacological treatments for Attention Deficit Disorder (ADD), more commonly referred to as Attention Deficit Hyperactivity Disorder (ADHD). These agents are classified as central nervous system stimulants and have been studied extensively for their efficacy in improving attention, impulse control, and hyperactivity symptoms in both children and adults with ADHD.

Multiple randomized, double-blind, placebo-controlled trials have demonstrated that stimulant medications significantly reduce core ADHD symptoms. Meta-analyses and systematic reviews, such as those published in journals like The Lancet Psychiatry and Journal of the American Academy of Child & Adolescent Psychiatry, consistently support the effectiveness of amphetamine-based treatments for ADHD. The neurobiological rationale is also well-understood: active amines increase synaptic concentrations of dopamine and norepinephrine in the prefrontal cortex, areas implicated in attention and executive function.

These medications are endorsed by major clinical guidelines, including those from the American Academy of Pediatrics and the National Institute for Health and Care Excellence (NICE), as first-line therapy for ADHD. Side effects and the potential for misuse are acknowledged, but the risk-benefit profile remains favorable when these drugs are used under medical supervision. In summary, the use of active amines for ADHD is strongly supported by robust scientific evidence and decades of clinical use.

More about Active Amines
More about Attention Deficit Disorder

Other health conditions supported by Active Amines

Attention Deficit Disorder
Cardiovascular Disease
Depression
Parkinson's Disease

Products containing Active Amines

We currently have no products on Vitabase that contain this ingredient.