Evidence supporting the use of: AHCC
For the health condition: Autoimmune Disorders

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Active Hexose Correlated Compound (AHCC) is a proprietary extract derived from the mycelia of shiitake mushrooms and has been studied primarily for its immunomodulatory properties. Its use in autoimmune disorders is primarily supported by preclinical and limited clinical evidence, rather than traditional use or robust clinical trials.

Animal studies and in vitro experiments suggest that AHCC can modulate the immune system by enhancing natural killer (NK) cell activity, promoting cytokine production, and possibly regulating T-cell responses. These immunomodulatory effects have led to interest in AHCC for conditions involving immune dysregulation, including autoimmune diseases. A few small pilot studies and case reports in humans have explored its effects in autoimmune contexts, such as inflammatory bowel disease and multiple sclerosis, but the data are preliminary and not definitive.

Importantly, most of the available clinical evidence for AHCC relates to its potential to enhance immune function in cancer patients or to reduce the side effects of chemotherapy, rather than to directly treat or manage autoimmune disorders. There is a lack of large, well-controlled human trials specifically investigating AHCC’s efficacy and safety in autoimmune diseases. Therefore, while there is some scientific rationale and early evidence supporting its immunomodulatory potential, the overall quality and quantity of evidence is limited, and routine clinical use in autoimmune disorders is not currently recommended.

More about AHCC
More about Autoimmune Disorders

Products containing AHCC

We currently have no products on Vitabase that contain this ingredient.