Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Amino acids have some scientific basis for use in supporting autoimmune disorders, primarily due to their roles in immune function, tissue repair, and modulation of inflammation. However, the evidence remains limited and largely preliminary, which is why the rating is 2 out of 5. Amino acids, particularly glutamine and arginine, are crucial for the maintenance and repair of the intestinal barrier, which is often compromised in autoimmune diseases such as Crohn’s disease and ulcerative colitis. Glutamine, in particular, has been shown in some small clinical studies and animal models to reduce gut permeability and modulate immune responses, potentially lowering inflammation.

Furthermore, amino acids like tryptophan and cysteine are important for synthesizing regulatory molecules (e.g., glutathione and serotonin) that may influence immune cell activity. Some research has investigated the supplementation of specific amino acids to help reduce symptoms or improve quality of life in conditions like rheumatoid arthritis, multiple sclerosis, and lupus, though results are mixed and often lack large-scale, well-controlled trials.

Overall, while there is a plausible scientific rationale for amino acid supplementation in autoimmune disorders and some encouraging early evidence, the approach is not yet strongly validated by robust clinical trials. Therefore, amino acids are sometimes used as adjunctive nutritional support rather than as primary therapy. More research is needed to clarify their efficacy and safety in this context.

More about amino acids
More about Autoimmune Disorders

Other ingredients used for Autoimmune Disorders

Other health conditions supported by amino acids

Products containing amino acids

Douglas Laboratories Free Form Amino