Achyranthes, particularly Achyranthes aspera, has a longstanding history of use in traditional medicine systems such as Ayurveda and Unani for the management of backache and related musculoskeletal complaints. The roots and whole plant are employed in various formulations, often as part of decoctions or topical preparations, to alleviate pain and inflammation. Traditional texts cite its purported anti-inflammatory and analgesic properties, attributing its effects to the presence of bioactive compounds like saponins, alkaloids, and flavonoids. However, while these historical uses are well documented, there is a paucity of high-quality clinical trials or robust scientific studies directly evaluating the efficacy of Achyranthes for backache in humans. Most available evidence consists of in vitro or animal studies that suggest anti-inflammatory and analgesic activity, but these findings do not directly translate to proven effectiveness in human back pain. Thus, the use of Achyranthes for backache is primarily justified by traditional practices rather than conclusive scientific validation.