Evidence supporting the use of: Salicin
For the health condition: Backache

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Salicin for Backache: Scientific Evidence

Salicin is a natural compound found in willow bark (Salix species) and is historically recognized as a precursor to aspirin (acetylsalicylic acid). Its use for pain and inflammation dates back centuries, particularly in traditional European medicine. Modern scientific research has investigated willow bark extracts, which contain salicin, for the treatment of musculoskeletal pain, including backache.

Several randomized controlled trials and meta-analyses have evaluated the efficacy of willow bark extract in patients with lower back pain. A notable study published in 2001 in the American Journal of Medicine demonstrated that standardized willow bark extract (providing 120–240 mg salicin daily) was more effective than placebo in reducing pain intensity in patients with chronic low back pain. Other meta-analyses and reviews, such as those in the Cochrane Database, have concluded that willow bark extract may provide modest short-term pain relief for backache compared to placebo, though the effect size is generally considered moderate.

Proposed mechanisms include the inhibition of prostaglandin synthesis, similar to nonsteroidal anti-inflammatory drugs (NSAIDs). Safety concerns are relatively low when used appropriately, though gastrointestinal side effects can occur, and it should be avoided in individuals allergic to aspirin or with certain medical conditions.

In summary, there is moderate scientific evidence supporting the use of salicin-containing willow bark extract for backache, justifying its current use for this indication, albeit with some limitations regarding long-term safety and efficacy.

More about Salicin
More about Backache

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capsaicinoids
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collagen
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vitamin D
vitamin D3
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sarsaparilla
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squawvine
gastrodia
atractylodes
papaya
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capsicum
mugwort
nut grass
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punarnava
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dioscorea
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morinda
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clematis
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Products containing Salicin

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