Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin B12, particularly in the form of methylcobalamin or hydroxycobalamin, has been studied as a potential adjunct therapy for Bell's Palsy, a condition characterized by acute facial nerve paralysis. The rationale for its use is based on the vitamin's essential role in nerve health, myelin sheath formation, and nerve regeneration. Several small randomized controlled trials and observational studies, primarily conducted in East Asia, have explored the efficacy of vitamin B12 (often in combination with corticosteroids or other B vitamins) in improving facial nerve function and recovery rates.

Some studies have reported that patients receiving vitamin B12 supplementation demonstrate faster or more complete recovery compared to those receiving standard care alone. However, these studies often have methodological limitations such as small sample sizes, lack of blinding, and heterogeneity in treatment protocols. Systematic reviews suggest that while there may be some benefit, the quality of evidence is low to moderate, and larger, high-quality trials are needed to draw firm conclusions.

Current clinical guidelines do not universally recommend vitamin B12 as standard therapy for Bell's Palsy, but it is sometimes used as an adjunct by clinicians, especially in populations where B12 deficiency is common. Overall, the evidence supporting B12's use in Bell’s Palsy is suggestive but not definitive, justifying a moderate evidence rating.

More about Vitamin B12 (Hydroxycobalamin)
More about Bell's Palsy

Other ingredients used for Bell's Palsy

Other health conditions supported by Vitamin B12 (Hydroxycobalamin)

Products containing Vitamin B12 (Hydroxycobalamin)