Evidence supporting the use of: Reishi mushroom
For the health condition: Benign Prostate Hyperplasia

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Reishi mushroom (Ganoderma lucidum) has been explored for its potential role in supporting or treating Benign Prostate Hyperplasia (BPH). While reishi has a long history of use in traditional Asian medicine for general vitality and immune support, specific interest in BPH stems from more recent scientific investigations. Some laboratory and clinical studies suggest that compounds in reishi, such as triterpenes and polysaccharides, may exhibit anti-androgenic and anti-inflammatory properties. These effects are relevant because BPH is associated with hormonal changes and inflammation in the prostate.

A small number of clinical trials have evaluated reishi extract in men with BPH. One randomized, double-blind, placebo-controlled study published in 2008 found that a low dose of reishi extract modestly improved International Prostate Symptom Scores (IPSS) compared to placebo. The researchers suggested that reishi's effects may be due to inhibition of 5-alpha-reductase, the enzyme responsible for converting testosterone to dihydrotestosterone (DHT), which promotes prostate enlargement. However, the sample size was small and the duration was limited.

Overall, while there is some preliminary scientific evidence to support the use of reishi mushroom for BPH, the quality and quantity of evidence are limited. More robust, large-scale clinical trials are needed to confirm efficacy and safety. Thus, the current level of scientific support is modest, warranting a rating of 2 out of 5.

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