Evidence supporting the use of: Stinging Nettle
For the health condition: Benign Prostate Hyperplasia

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Stinging Nettle (Urtica dioica) has been studied for its potential benefits in managing symptoms of Benign Prostate Hyperplasia (BPH). Several clinical trials and reviews suggest that extracts from the root of stinging nettle can moderately improve lower urinary tract symptoms associated with BPH, such as reduced urinary flow and frequent urination. The mechanism is not fully understood, but research indicates that nettle root may inhibit the activity of sex hormone-binding globulin and interfere with enzymes involved in prostate cell metabolism, such as aromatase and 5-alpha-reductase. Some studies also suggest anti-inflammatory effects.

A 2005 double-blind, placebo-controlled study published in the journal Journal of Herbal Pharmacotherapy found that men with BPH who took nettle root extract for six months had significantly improved symptoms compared to placebo. Meta-analyses and systematic reviews (e.g., European Association of Urology guidelines) acknowledge that nettle root is among the phytotherapeutic agents with evidence for mild to moderate efficacy in reducing BPH symptoms, though it is generally considered less effective than pharmaceutical treatments like alpha-blockers.

Overall, while not universally endorsed and with variation in study quality, the use of stinging nettle root for BPH is supported by moderate scientific evidence, especially for symptom relief, and is included in some European phytotherapy guidelines.

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