Evidence supporting the use of: Abrus
For the health condition: Bites and Stings

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Abrus, most commonly referring to Abrus precatorius (jequirity, rosary pea), has a long history of use in traditional medicine systems across Asia and Africa. Traditional healers have sometimes used preparations of Abrus leaves or seeds, often after detoxification processing, to treat bites and stings, including those from snakes and insects. The rationale behind its use may stem from its perceived anti-inflammatory, analgesic, or "drawing" properties. In Ayurveda and folk medicine, topical application of crushed leaves or poultices is documented for skin ailments and bites. However, the seeds of Abrus contain abrin, a highly toxic ribosome-inactivating protein, and are potentially lethal if ingested or improperly prepared, leading to severe poisoning or death.

There is currently no robust scientific evidence or clinical trials validating the efficacy or safety of Abrus in treating bites or stings. Some in vitro studies have examined extracts for anti-inflammatory or antimicrobial activity, but these do not directly support use for envenomation or venom neutralization. Therefore, while the use of Abrus for this purpose is rooted in tradition, it is not supported by scientific validation and carries significant risk due to toxicity. Modern medical guidance strongly advises against using Abrus preparations for bites and stings, emphasizing the danger of abrin poisoning.

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