Evidence supporting the use of: Black Nightshade
For the health condition: Bites and Stings

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Black Nightshade (Solanum nigrum) has been used in various traditional medicine systems, including Ayurveda and folk medicine in Africa, Asia, and Europe, for the management of bites and stings. The plant’s leaves and berries have been applied topically to the skin in an attempt to reduce pain, inflammation, and the effects of insect bites or minor animal stings. Historical texts and ethnobotanical surveys document such uses, often in the form of poultices or crushed fresh plant material. The rationale behind its use is largely based on its purported anti-inflammatory and analgesic properties, which could theoretically provide symptomatic relief.

However, scientific validation for these uses is minimal. While in vitro and animal studies suggest that some constituents of Black Nightshade (such as solanine and related alkaloids) may have anti-inflammatory and antioxidant effects, there is little to no direct clinical evidence specifically supporting its efficacy for bites or stings in humans. Furthermore, the plant contains toxic compounds and improper use can cause poisoning. Therefore, while the traditional use of Black Nightshade for bites and stings is well-documented, it is not strongly supported by scientific research, and safety concerns limit its recommendation in modern herbal practice.

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