Evidence supporting the use of: Madder
For the body system: Bladder
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Madder (Rubia cordifolia) has a long history of use in traditional systems of medicine, particularly Ayurveda and Unani medicine, for supporting urinary and bladder health. Traditionally, madder root has been used as a diuretic and for its purported ability to help dissolve or alleviate urinary stones (urolithiasis), support bladder function, and promote the elimination of toxins through the urinary tract. The coloring compounds (such as alizarin and purpurin) and other phytochemicals are believed by traditional practitioners to have beneficial effects on the urinary system.
However, scientific evidence supporting madder’s effectiveness for bladder health is limited. While some in vitro and animal studies have explored its potential anti-inflammatory, antimicrobial, and anti-urolithiatic properties, robust clinical trials in humans are lacking. The historical use is well documented, but evidence from modern research is not strong enough to warrant a higher score. Furthermore, madder has some safety concerns, as certain compounds have shown potential carcinogenicity in animal studies, leading to regulatory restrictions in some countries. In summary, while madder’s use for bladder support is justified by tradition and historical precedent, scientific validation is minimal.
Other ingredients that support Bladder
AbutaAchyranthes
Aerva lanata
Agrimonia pilosa
Agrimony
Akebia
Alchemilla
Alchornea
Aletris
Alisma
Anserina
arbutin
asparagus
aucubin
bael
Baliospermum
balsam
Bassia scoparia
bearberry
Bergenia
bergenin
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beta-sitosterol
birch
bistort
black poplar
Blepharis
Boerhavia diffusa
boldo
Bombax
Borassus aethiopum
bottle gourd
Brazilian peppertree
buchu
carrapicho
cedar
chanca piedra
chickweed
cleavers
Cnidium
Coconut Water
coix
common thatching grass
corktree
cornflower
cornsilk
costus
couch grass
cranberry
cranesbill
Crinum latifolium
cubeb
Cucurbita
D-mannose
damiana
dandelion
Dianthus
Didymocarpus
Dimethyl sulfoxide (DMSO)
DL-Methionine
dodder
Dwarf Nettle
Echinodorus
elephant\'s head
Erigeron
European five-finger grass
Euryale seed
fireweed
fleabane
fringed pink
fringetree
fu ling
fungus
giant blazingstar
Glechoma hederacea
Glycosaminoglycans
Gnaphalium
gokhru
golden ragwort
golden shower tree
goldenrod
goldenseal
goldthread
gravel root
Guazuma ulmifolia
guelder rose
heather
Hedychium spicatum
herbal blend (proprietary)
horseradish
horsetail
hydrangea
Hygrophila
Indian bael
Indian sarsparilla
isothiocyanates
Japecanga
Jatoba
Java tea
joe-pye
juniper berries
Kalanchoe pinnatum
Kigelia africana
knotgrass
Kochia
labrador tea
Leptospermum scoparium
Lindera
Long Buchu
Longleaf buchu
lophatherum leaf
lovage
Lycopodium
Lygodium
Lysimachia
madder
Maidenhair Fern
mallow
Malva sylvestris
mannose
manzanita
Marshmallow
Matico
Maytenus ilicifolia
Meadowsweet
Methenamine
Mondo grass
Mucilage
Mugwort
Nasturtium
Nettle
Nigella seed
nut grass
Ocotillo
Operculina turpethum
Ovate Buchu
Palo Azul
Pareira
parsley
pear
Pedalium
Pellitory
Phellodendron
Phlomis umbrosa
Phragmites
Phyllanthus
Pipsissewa
Plantago
plantain
Polyporus
Potentilla
Pulsatilla
pumpkin
punarnava
pygeum
Pyrola
Pyrrosia
queen of the meadow
Rhus glabra
Rosa laevigata
Rubus
Rupturewort
Sanguisorba
Sargentodoxa
sarsaparilla
Sassafras
saw palmetto
Scirpus
Sensitive Plant
shepherd's purse
Silverweed
Smartweed
Soft rush
Sparganium
Speedwell
Spiny Restharrow
squawvine
Stachytarpheta cayennensis
Stereospermum
Stone Root
Sweet Woodruff
Taraxacin
Taraxacum
Taraxol
Tiger Nut
Toadflax
Trailing Arbutus
Turtle Head
Varuna
Veronica
Viburnum
Wax Gourd
White Dead Nettle Flower
White oak
White Poplar
Wood betony
Yarrow
Yerba Mansa
Yin Chen
Zedoary
