Yerba Mansa (Anemopsis californica) has a long history of use in traditional herbal medicine, particularly among Native American groups in the southwestern United States and northern Mexico. It has been used as an herbal remedy for a variety of ailments, including those affecting the urinary tract and bladder. Traditional uses include decoctions, infusions, and poultices made from the root or rhizome of the plant, which were believed to address symptoms such as urinary tract discomfort, inflammation, and infection. The plant’s astringent and antimicrobial properties, noted in ethnobotanical literature, are thought to contribute to its historical use for bladder and urinary tract health.

However, despite this traditional reputation, scientific evidence supporting Yerba Mansa’s efficacy for bladder health is limited. There are few, if any, rigorous clinical studies published on its effects in humans for this purpose. Some laboratory studies have observed mild antimicrobial or anti-inflammatory properties in plant extracts, but these findings are preliminary and not directly tied to bladder health or infection in clinical contexts. Thus, the use of Yerba Mansa for supporting the bladder is justified mainly by traditional practice, with a relatively low but existent evidence rating due to the lack of robust scientific studies.