Evidence supporting the use of: Lactobacillus brevis
For the health condition: Bladder Infection

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lactobacillus brevis is a species of probiotic bacteria found in fermented foods and the human microbiota, including the genitourinary tract. The use of L. brevis to support or treat bladder infections (urinary tract infections, or UTIs) is based on the broader concept of using probiotics to restore and maintain healthy urogenital flora, which may help inhibit the growth of pathogenic bacteria responsible for UTIs. While the most extensively studied Lactobacillus species for this indication are L. rhamnosus and L. reuteri, some research has explored the potential role of L. brevis as well.

Preclinical studies and a few small clinical trials suggest that certain Lactobacillus strains, including L. brevis, may adhere to uroepithelial cells, produce antimicrobial substances (like lactic acid and bacteriocins), and competitively exclude uropathogens. However, direct clinical evidence supporting L. brevis specifically for the prevention or treatment of bladder infections is limited and not robust. Most systematic reviews and guidelines highlight the need for more high-quality research before probiotics, particularly specific strains like L. brevis, can be routinely recommended for UTIs.

In summary, while there is a scientific rationale and some preliminary evidence for the use of L. brevis in supporting urinary tract health, the quality and quantity of supporting evidence for its use in bladder infections is currently weak (rated 2/5). Its use is not primarily rooted in tradition, but rather in emerging probiotic science, warranting further investigation.

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