Evidence supporting the use of: Lactobacillus (unspepcified)
For the health condition: Bladder Infection

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lactobacillus species are commonly used probiotics, and their use in supporting or preventing bladder infections (urinary tract infections, UTIs) has some basis in scientific research, though evidence remains limited and somewhat inconsistent. The rationale stems from the fact that Lactobacillus bacteria are a dominant part of the healthy vaginal microbiome, where they help maintain an acidic environment and inhibit the growth of uropathogenic bacteria such as Escherichia coli. Disruption of the Lactobacillus population (for example, by antibiotics) is associated with higher risk of UTIs, especially in women.

Several small clinical trials and observational studies have investigated whether oral or intravaginal administration of Lactobacillus can reduce UTI recurrence. Some strains (notably L. crispatus) show promise in reducing UTI recurrence rates, but benefits are modest and not all studies show statistically significant results. A 2015 Cochrane review concluded that while there is some evidence for benefit, the quality of the evidence is low and larger, well-controlled studies are needed. Guidelines from most professional organizations do not currently endorse probiotics as a primary preventive or treatment strategy for bladder infections, but do recognize their safety and potential as adjuncts or for patients seeking non-antibiotic options.

In summary, there is limited scientific evidence supporting the use of Lactobacillus to prevent recurrent bladder infections, primarily in women, but more research is needed and its use is not yet considered standard of care.

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