Lophatherum leaf, also known as Lophatherum gracile or "Danzhuye" in traditional Chinese medicine (TCM), is traditionally used to clear heat and promote urination, making it a common herbal remedy for conditions like urinary tract infections (UTIs) and bladder infections. In TCM, Danzhuye is believed to eliminate "heat" from the heart and small intestine channels, which often manifests as symptoms such as irritability, mouth sores, and painful urination. Its diuretic action is thought to help flush out pathogens and alleviate discomfort associated with bladder infections.

While there is some laboratory research indicating mild antibacterial and anti-inflammatory effects of Lophatherum leaf extracts, clinical evidence in humans is sparse or lacking. The majority of its use for bladder infection is rooted in centuries-old TCM practice rather than modern scientific validation. Most contemporary herbal formulas targeting urinary tract infections in East Asia may include Danzhuye in combination with other herbs for synergistic effects.

In summary, the use of Lophatherum leaf for bladder infections is justified by traditional use, especially within the context of TCM theory and practice. However, there is limited direct scientific evidence or rigorous clinical trials to confirm its efficacy for this condition, so its evidence rating is modest.