Evidence supporting the use of: Trisodium citrate
For the health condition: Bladder Infection
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Trisodium citrate is used as a urinary alkalinizer, which means it helps to make the urine less acidic. This effect can provide symptomatic relief in people suffering from bladder infections (cystitis), particularly by reducing the burning sensation that often accompanies urination. Trisodium citrate acts by increasing the pH of urine, which can inhibit the growth of certain bacteria that prefer acidic environments, although it does not have direct antibacterial effects.
There is some scientific rationale and clinical usage for trisodium citrate in managing the symptoms of lower urinary tract infections. It is included in some over-the-counter cystitis relief products in various countries, such as the UK. However, the evidence supporting its effectiveness is limited, mostly consisting of small clinical studies and expert consensus rather than large, high-quality randomized controlled trials. The symptomatic benefit is generally attributed to the alkalinization of urine, thereby reducing irritation of the inflamed bladder wall.
It is important to note that trisodium citrate does not treat the underlying infection and should not be considered a substitute for antibiotics when these are indicated. The main benefit is symptomatic relief, and the evidence base for its efficacy is modest. Therefore, it receives a rating of 2 for scientific support in the context of bladder infection management.
Other ingredients used for Bladder Infection
bearberryberberine
coconut milk
cranberry
cucumber
turmeric
D-mannose
echinacea purpurea
goldenseal
horseradish
Indian tinospora
lactobacillus acidophilus
lactobacillus brevis
lactobacillus crispatus
lactobacillus fermentum
lactobacillus gasseri
lactiplantibacillus plantarum
lactobacillus reuteri
lactobacillus salivarius
lophatherum leaf
methenamine
oregano
oregon grape
phellodendron amurense
prebiotic blend (proprietary)
scrophularia root
slippery elm bark
vitamin C
water
sarsaparilla
squawvine
shen-chu
punarnava
goldenrod
lemongrass
juniper berries
dodder
cornsilk
buchu
couch grass
hydrangea
cleavers
wood betony
herbal blend (proprietary)
indigo leaves
gravel root
akebia
Ardisia
Arbutin
Agave
Allicin
Abrus
Alchornea
Aerva lanata
Andrographis
Alisma
Abuta
Amor seco
Bermuda Grass
Big Quaking Grass
berry
Bur-Reed
Bacteria
Bassia scoparia
Boerhavia diffusa
Cucurbita
Cnidium
Chinese Raisintree
Chanca Piedra
Costus
Echinacea
Essential Oil Blend
Sumac
Other health conditions supported by Trisodium citrate
Acid IndigestionBladder Infection
Kidney Stones
Overacidity