Evidence supporting the use of: Goldthread (unspecified)
For the health condition: Bleeding (external)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Goldthread, commonly referring to species such as Coptis chinensis (Chinese goldthread) or Coptis trifolia (American goldthread), has a longstanding use in traditional Chinese medicine and other herbal systems. Historically, it has been employed for its antimicrobial, anti-inflammatory, and hemostatic (bleeding-stopping) properties. Classic Chinese medical texts describe the use of Coptis species, often in powdered or decocted form, for managing bleeding—especially in cases of external wounds, ulcers, or skin lesions. The herb’s yellow rhizome is rich in isoquinoline alkaloids, particularly berberine, which has been associated with astringent actions and wound-healing in traditional practice.

Despite its historical usage, modern scientific validation specific to the management of external bleeding is limited. While some laboratory studies suggest that berberine and related compounds may possess mild astringent and antimicrobial effects that could theoretically aid wound healing and reduce bleeding, robust clinical trials are lacking. The evidence base is therefore rooted in tradition rather than rigorous scientific demonstration. Nonetheless, Goldthread continues to be included in traditional herbal formulas for topical application in East Asian medicine, reflecting its perceived value in wound care across centuries.

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