Evidence supporting the use of: Sangre de Grado
For the health condition: Bleeding (external)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 4

Sangre de Grado (also known as Dragon's Blood, derived from the sap of Croton lechleri) has a long history of traditional use among indigenous peoples of the Amazon rainforest for treating external bleeding and promoting wound healing. The bright red sap is commonly applied directly to cuts, abrasions, and other skin injuries. Ethnobotanical records, such as those compiled by Dr. James Duke and various ethnopharmacological surveys, document its frequent use as a topical hemostatic agent. The sap quickly dries to form a protective barrier, which helps to stop bleeding and shield wounds from infection.

Scientific investigations have identified several active compounds in Sangre de Grado, including proanthocyanidins, taspine, and other alkaloids, which may contribute to its wound-healing and antimicrobial effects. Laboratory and animal studies have demonstrated that the sap can reduce bleeding, promote faster wound closure, and inhibit bacterial growth. However, while these studies support the traditional use and suggest a plausible mechanism of action, large-scale, high-quality clinical trials in humans are still limited. Most of the evidence remains preclinical or anecdotal, though it is generally considered safe when used topically. Thus, while its use for external bleeding is primarily grounded in traditional practice, this is bolstered by some scientific data.

More about Sangre de Grado
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