Evidence supporting the use of: Allantoin
For the health condition: Blisters

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Allantoin is a compound commonly found in skin care products due to its moisturizing, keratolytic (exfoliating), and wound-healing properties. While its use in treating or supporting the healing of blisters is not as extensively studied as its general wound-healing effects, there is some scientific evidence that supports its role in promoting epithelialization (the formation of new skin) and tissue repair. Allantoin has been shown in laboratory and clinical studies to stimulate cell proliferation and increase the water content of the extracellular matrix, which can aid in skin recovery after minor injuries, including blisters.

However, the evidence specifically targeting its efficacy in blister treatment is limited. Most available research covers its benefits in promoting healing in minor wounds, abrasions, and skin irritations rather than blisters per se. Its inclusion in over-the-counter blister ointments and wound-healing creams is largely based on its proven safety profile and its documented benefits in accelerating skin repair processes. Overall, while there is a scientific rationale for allantoin’s use in supporting blister recovery, the direct evidence for this specific indication is not robust, resulting in a moderate evidence rating.

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Products containing Allantoin

We currently have no products on Vitabase that contain this ingredient.