Relationship: Blood and manganese

Evidence supporting the use of: Manganese
For the body system: Blood

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Manganese is an essential trace mineral that plays a significant role in several physiological processes, including those related to the blood system. Its primary scientific justification for inclusion in supplements targeting the blood is its role as a cofactor for enzymes involved in the formation of connective tissue, bone, blood clotting factors, and the metabolism of carbohydrates, amino acids, and cholesterol. Most notably, manganese is a component of the antioxidant enzyme superoxide dismutase (MnSOD), which protects blood cells from oxidative damage.

Manganese is also necessary for the synthesis of prothrombin, a key protein involved in blood clotting. However, manganese is not directly involved in hemoglobin synthesis or iron metabolism, which are more central to the blood’s oxygen-carrying capacity. Deficiency in manganese is rare but can lead to impaired growth, skeletal abnormalities, and altered carbohydrate and fat metabolism. There is limited evidence that manganese deficiency alone leads to significant blood disorders in humans.

Overall, while manganese is scientifically validated as an essential nutrient for various aspects of human health, its specific use to “support the blood” is somewhat indirect and generally limited to its enzymatic and clotting roles. There is not strong evidence that manganese supplementation benefits the blood system in individuals without a deficiency. Thus, the evidence rating is moderate.

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Other body systems supported by manganese

Blood
Glandular System
Immune System
Joints
Mitochondria
Nerves
Skeletal System (Bones)
Skin

Products containing manganese

Health Concerns

Brands

Evidence supporting the use of: Manganese
For the body system: Blood

Table of Contents

Synopsis

Other ingredients that support Blood

Other body systems supported by manganese

Products containing manganese

Health Concerns

Brands

Evidence supporting the use of: ManganeseFor the body system: Blood

Table of Contents

Synopsis

Other ingredients that support Blood

Other body systems supported by manganese

Products containing manganese

Evidence supporting the use of: Manganese
For the body system: Blood