Evidence supporting the use of: Angelica gigas nakai
For the health condition: Blood Clots (prevention of)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Angelica gigas Nakai, commonly known as Korean angelica, has been traditionally used in East Asian medicine for various ailments, including blood-related disorders. Scientific studies, mostly preclinical (in vitro and animal studies), suggest that extracts from the root contain active compounds such as decursin and decursinol angelate, which may exert antithrombotic (blood clot-preventing) and anticoagulant effects. These compounds appear to inhibit platelet aggregation and suppress coagulation pathways, both of which are mechanisms involved in the formation of blood clots.

For example, a 2003 study in Thrombosis Research demonstrated that decursin isolated from A. gigas inhibited platelet aggregation and thrombus formation in rats. Other studies have shown that extracts can modulate blood flow and reduce clot formation in animal models. However, there are no large-scale human clinical trials confirming efficacy or safety for the prevention of blood clots in humans.

In summary, while the traditional use of Angelica gigas for blood-related conditions exists, its application for blood clot prevention is supported by some preliminary scientific evidence—primarily from laboratory and animal studies. The absence of robust human clinical data limits the evidence rating to 2 out of 5. Anyone considering its use for this purpose should consult a healthcare professional due to possible drug interactions and safety concerns.

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