Evidence supporting the use of: Cocoa
For the health condition: Blood Clots (prevention of)
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Cocoa, derived from the beans of Theobroma cacao, has been investigated for its potential cardiovascular benefits, including the prevention of blood clots. Scientific studies suggest that cocoa is rich in flavonoids, particularly epicatechin and catechin, which exhibit antiplatelet and vasodilatory effects. These compounds may inhibit platelet aggregation—a key step in blood clot formation—by modulating nitric oxide production and reducing the activity of clotting factors.
Several clinical trials and observational studies support the idea that moderate consumption of cocoa or dark chocolate can reduce platelet activation and improve endothelial function. For example, a randomized controlled trial published in the American Journal of Clinical Nutrition found that short-term intake of flavanol-rich cocoa reduced platelet activation in healthy subjects. Similarly, epidemiological studies have linked higher chocolate consumption with reduced risk of cardiovascular events, some of which are due to thrombotic (clot-related) mechanisms.
However, it is important to note that most evidence comes from studies on dark chocolate or cocoa extracts, not isolated cocoa supplements, and effects can vary based on dose and flavonoid content. While cocoa’s blood-thinning effects are mild compared to pharmaceutical anticoagulants, the scientific evidence does support a modest preventive effect on blood clot formation, particularly as part of a balanced diet. More research is needed to define optimal consumption and to identify who may benefit most.
Other ingredients used for Blood Clots (prevention of)
AjoeneAlgae
Allicin
Angelica
Auricularia
black cumin
bromelain
capsicum
cayenne pepper
Chinese salvia root
chocolate
cinnamon
cocoa
Curcuma
curcumin
Curcuminoid
Cyathula
danshen
dextran
Diosmin
dong quai root
eicosapentaenoic acid
fiber
fish oil
fish protein
flavonoids
flavonols
ganoderma
garlic
garlic bulb
hesperidin
horse chestnut
kiwi
Ligusticum
Ligustrazin
lumbrokinase
Nattokinase
Nattozimes
omega-3 fatty acids
onion
Phaeophyceae
phenolic compounds
polyphenols
polyunsaturated fat
Pycnogenol
quercetin
Rubia cordifolia
rutin
Sanguisorba
seaweed
Serrapeptase
shiitake mushroom
Sulfated polysaccharide
Sweet Clover
Tanshinone
Taxillus chinensis
Troxerutin
turmeric
Xanthine
Xanthophyll
Xantinol Nicotinate
Zucchini
Other health conditions supported by cocoa
Alzheimer's DiseaseAnxiety
Anxiety Disorders
Arteriosclerosis
Asthma
Athletic and Exercise Aids
Blood Clots (prevention of)
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cardiovascular Disease
Cholesterol (high)
Circulation (poor)
Circulation (to the brain)
Concentration (poor)
Depression
Diabetes
Digestion (poor)
Fatigue
Free Radical Damage
Hypertension
Inflammation
Memory and Brain Function
Mood Swings
Nervousness
Stress
Triglycerides (high)
Weight Loss
