Evidence supporting the use of: Rhubarb
For the health condition: Blood in Stool

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Rhubarb (Rheum spp.) has been used in traditional Chinese medicine (TCM) for centuries, particularly for gastrointestinal complaints, including symptoms such as blood in stool (hematochezia). In TCM, rhubarb is believed to have purgative and "blood-cooling" properties, and is often included in herbal formulas intended to clear heat and remove stasis, which are thought to contribute to bleeding in the digestive tract. Historical texts like the "Shennong Bencao Jing" and later pharmacopoeias describe its use in treating various forms of internal bleeding, including gastrointestinal bleeding.

From a modern scientific perspective, there is limited but emerging evidence that rhubarb and its active compounds (like anthraquinones) may have hemostatic effects, anti-inflammatory activity, and the potential to protect the intestinal mucosa. Some small studies and animal experiments suggest that rhubarb extracts may reduce bleeding and improve mucosal integrity in models of colitis or gastrointestinal injury. However, the clinical evidence in humans for rhubarb's effectiveness specifically for blood in stool is sparse, and most of the justification for its use remains rooted in tradition rather than robust clinical trials. Additionally, rhubarb can have strong laxative effects, which may not be desirable in cases of active gastrointestinal bleeding.

In summary, the use of rhubarb for blood in stool is primarily supported by traditional use, with only low-quality or preliminary scientific evidence available. More rigorous clinical studies would be required to validate its efficacy and safety for this specific condition.

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