Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Rubia cordifolia, commonly known as Indian madder or Manjistha, has a long history of use in Ayurvedic and traditional Chinese medicine. Traditionally, it has been employed to "purify" the blood and treat conditions believed to be caused by "blood impurities," which may sometimes be referenced as "blood poisoning" in older or non-scientific texts. In Ayurveda, Manjistha is considered a potent herb for detoxification, skin health, and promoting healthy blood flow. Practitioners have used it to address chronic skin conditions, ulcers, and infections, which could, in severe cases, be associated with systemic infection or sepsis ("blood poisoning").

However, the scientific evidence supporting its use specifically for treating blood poisoning (systemic bacterial infection or sepsis) is limited. Modern pharmacological studies have identified anti-inflammatory, antioxidant, and antimicrobial properties in Rubia cordifolia extracts, but these studies are mostly in vitro or in animal models and do not directly address human sepsis. There are no robust clinical trials validating its efficacy for this life-threatening condition. The traditional use likely stems from its broader application in managing skin infections and supporting wound healing, rather than from any proven ability to treat systemic infection. Therefore, while its use is justified by tradition, it lacks strong scientific support for use in blood poisoning as defined by modern medicine.

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