Evidence supporting the use of: 2, 17a-dimethyl-17b-hydroxy-5a-androst-2-ene
For the health condition: Body Building

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

2,17a-dimethyl-17b-hydroxy-5a-androst-2-ene, also known as "methyldrostanolone" or "superdrol," is a synthetic orally active anabolic-androgenic steroid (AAS). Its use in bodybuilding is primarily supported by scientific understanding of its pharmacological effects. Superdrol is structurally similar to dihydrotestosterone (DHT) and has been shown to possess strong anabolic properties with relatively low androgenic activity. It is used by bodybuilders to promote muscle growth, enhance strength, and improve overall physique.

Scientific literature and anecdotal reports affirm its potency in increasing lean muscle mass and strength over short cycles. However, formal peer-reviewed studies on its efficacy and safety in healthy athletes are limited, as most data come from user reports and a few controlled animal or cell studies. The anabolic effect is due to its ability to bind androgen receptors and stimulate protein synthesis. Nonetheless, it carries significant risks, including liver toxicity (due to 17a-methylation), suppression of natural testosterone production, and potential cardiovascular side effects.

While the mechanism is scientifically validated, the lack of robust human clinical trials means that the evidence for its safe and effective use in bodybuilding is moderate but not high. Its use is banned by most sports organizations and is associated with legal and health risks. In summary, the support for its use is based on pharmacological rationale and user experience rather than comprehensive clinical trials.

More about 2, 17a-dimethyl-17b-hydroxy-5a-androst-2-ene
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Other health conditions supported by 2, 17a-dimethyl-17b-hydroxy-5a-androst-2-ene

Athletic and Exercise Aids
Body Building
Wasting

Products containing 2, 17a-dimethyl-17b-hydroxy-5a-androst-2-ene

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