Evidence supporting the use of: 2a, 17a-dimethyl-17b-hydroxy-5a-androstan-3-one
For the health condition: Body Building

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

2a, 17a-dimethyl-17b-hydroxy-5a-androstan-3-one, also known as methyl-1-testosterone or M1T, is an orally active anabolic-androgenic steroid (AAS). Its use in bodybuilding is primarily supported by scientific understanding of its pharmacological effects, not tradition. M1T is a synthetic derivative of dihydrotestosterone (DHT) that exhibits potent anabolic activity. Peer-reviewed studies and anecdotal reports indicate that it significantly increases muscle mass and strength when used in conjunction with resistance training, due to its ability to enhance protein synthesis and nitrogen retention in muscle tissue. As a methylated AAS, it is orally bioavailable, making it attractive for non-injectable use among athletes and bodybuilders.

However, the evidence base is largely extrapolated from general AAS research and limited clinical studies on M1T itself. Its anabolic potency is reported to be several times greater than testosterone, with a relatively low androgenic effect. Despite these effects, M1T use is associated with significant health risks, including hepatotoxicity, suppression of natural testosterone production, negative lipid profile changes, and other serious side effects. M1T was never approved for medical use and has been classified as a controlled substance in many countries. Its use in bodybuilding is banned by most sports organizations. Nonetheless, the scientific rationale for its muscle-building properties is well established, though overshadowed by safety concerns.

More about 2a, 17a-dimethyl-17b-hydroxy-5a-androstan-3-one
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7-Keto-DHEA
Acetyl L-carnitine
adenosine 5-triphosphate disodium (ATP)
alpha-ketoglutarate (AKG)
amino acids
anchovies
ashwagandha
aspartic acid
beta-alanine
bovine
branched-chain amino acids
caffeine
capsaicinoids
coleus forskohlii
conjugated linoleic acid (CLA)
creatine monohydrate
curcumin
gelatin
ginseng
greens blend (proprietary)
hydroxycitric acid
l-isoleucine
iron
L-cysteine
L-glutamine
L-glycine
L-leucine
L-methionine
L-Ornithine
L-valine
magnesium
maltodextrin
milk
omega-3 fatty acids
ornithine alpha-ketoglutarate
protein
Almond fruit
vitamin D
whey protein
zinc
wheat germ
Algae
chickpea protein
brown rice protein
AMP-activated protein kinase (AMPK)
1,3,7-Trimethylpurine-2,6-dione
2a, 17a-dimethyl-17b-hydroxy-5a-androstan-3-one
4-DHEA
Arginine Alpha Ketoglutarate
Arachidonic Acid
Arginine malate
Alpha glyceryl
Alpha-ketoisocaproic acid
Adenosine triphosphate (ATP)
Algal protein
Alpha hydroxyisocaproic acid
Anti-aromatase
Animal protein
Beef Protein
Beef
Beef liver
Bovine Protein
beta-lactoglobulin
Ba Ji Tian
banana
Chia seed
Casein
Cardarine
Citrus
Capsaicin
Capsiate
Chicken
D-Aspartic Acid
Dihydrocapsiate
Deer Velvet
D-Ribose
Dextrose
Eurycomanone
Egg
Eurycoma Longifolia
Ecdysteroids
Elthyl-Alpha-Guanido-Methyl-Ethanoate
Ecdysterone
Egg protein
Fungus
Fadogia agrestis
Forskolin
glucose
Hydroxymethylbutyrate
HMB Hydroxymethylbutyrate
Isoleucine
Ketosterones
leucine alpha-ketoglutarate
Lactalbumin
Lactoglobulin
Lipids
Marine Protein
Milk Protein
Phytoecdysteroid
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Phosphatidic Acid
Palatinose
Propionate ester
Peptides
Rhaponticum
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yohimbine
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Other health conditions supported by 2a, 17a-dimethyl-17b-hydroxy-5a-androstan-3-one

Body Building
Wasting

Products containing 2a, 17a-dimethyl-17b-hydroxy-5a-androstan-3-one

We currently have no products on Vitabase that contain this ingredient.