Evidence supporting the use of: Alpha lipoic acid
For the health condition: Body Building

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Alpha lipoic acid (ALA) is an antioxidant that has gained popularity in the bodybuilding community, primarily for its potential to improve glucose uptake and reduce oxidative stress. The justification for its use is based on scientific rationale, but high-quality human studies specifically in bodybuilders are limited, so the overall evidence rating is modest.

ALA is a naturally occurring compound involved in mitochondrial energy metabolism. Some studies suggest that ALA can enhance glucose uptake in muscle cells by increasing insulin sensitivity, which theoretically could support glycogen storage and muscle recovery after workouts. This mechanism is attractive to bodybuilders seeking to maximize muscle growth and recovery. Additionally, ALA's antioxidant properties may help reduce exercise-induced oxidative damage, possibly aiding recovery and reducing muscle soreness.

However, while small clinical trials and animal studies support these mechanisms, direct evidence in the context of bodybuilding (e.g., improved muscle mass, strength, or performance) is sparse. Most available studies use mixed populations or focus on individuals with metabolic disorders rather than healthy athletes. ALA is sometimes included in "nutrient partitioning" supplements with the aim of enhancing muscle gain and fat loss, but robust, long-term human data in athletes are lacking.

In summary, there is a scientific basis for the use of alpha lipoic acid in bodybuilding, mainly related to glucose metabolism and antioxidant effects, but the quality and quantity of direct evidence supporting its effectiveness for enhancing muscle growth or performance in bodybuilders remains limited.

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Other ingredients used for Body Building

7-Keto-DHEA
Acetyl L-carnitine
adenosine 5-triphosphate disodium (ATP)
alpha-ketoglutarate (AKG)
amino acids
anchovies
ashwagandha
aspartic acid
beta-alanine
bovine
branched-chain amino acids
caffeine
capsaicinoids
Coleus forskohlii
conjugated linoleic acid (CLA)
creatine monohydrate
curcumin
gelatin
ginseng
greens blend (proprietary)
hydroxycitric acid
l-isoleucine
iron
L-cysteine
L-glutamine
L-glycine
L-leucine
L-methionine
L-ornithine
L-valine
magnesium
maltodextrin
Milk
omega-3 fatty acids
ornithine alpha-ketoglutarate
protein
Almond fruit
vitamin D
Whey protein
Zinc
wheat germ
Algae
chickpea protein
brown rice protein
AMP-activated protein kinase (AMPK)
1,3,7-Trimethylpurine-2,6-dione
4-DHEA
arginine alpha ketoglutarate
arachidonic acid
Arginine malate
Alpha glyceryl
Alpha-ketoisocaproic acid
Adenosine triphosphate (ATP)
Algal protein
Alpha hydroxyisocaproic acid
anti-aromatase
animal protein
Beef Protein
beef
Beef liver
bovine protein
beta-lactoglobulin
ba ji tian
banana
chia seed
casein
cardarine
Citrus
capsaicin
capsiate
D-Aspartic Acid
dihydrocapsiate
deer velvet
D-Ribose
dextrose
eurycomanone
egg
Eurycoma Longifolia
ecdysteroids
Ethyl-Alpha-Guanido-Methyl-Ethanoate
ecdysterone
Egg protein
fungus
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forskolin
glucose
hydroxymethylbutyrate
HMB hydroxymethylbutyrate
Isoleucine
ketosterones
leucine alpha-ketoglutarate
lactalbumin
lactoglobulin
lipids
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propionate ester
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Products containing alpha lipoic acid

Vitabase ALA/ALC 750mg
Thorne Alpha-Lipoic Acid
Pure Encapsulations Alpha Lipoic Acid 100 mg
Pure Encapsulations Alpha Lipoic Acid 100 mg
Douglas Laboratories Alpha-Lipoic Acid
Pure Encapsulations Alpha Lipoic Acid 200 mg
Pure Encapsulations Alpha Lipoic Acid 200 mg
Pure Encapsulations Alpha Lipoic Acid 400 mg
Pure Encapsulations Alpha Lipoic Acid 400 mg
Pure Encapsulations Alpha Lipoic Acid 600 mg
Pure Encapsulations Alpha Lipoic Acid 600 mg
Pure Encapsulations Amino-NR
Pure Encapsulations Athletic Nutrients
Douglas Laboratories Berberine Balance
Designs For Health Berberine Synergy™
Vitabase Blood Sugar Formula
Designs For Health Detox Antiox™
Designs For Health Detoxification Support Packets
Thorne Diabenil
Pure Encapsulations DIM Detox
Pure Encapsulations GlucoFunction
Pure Encapsulations GlucoFunction
Pure Encapsulations Glucose Support Formula
Pure Encapsulations Glucose Support Formula
Integrative Therapeutics Glycemic Manager
Pure Encapsulations HM Complex
Pure Encapsulations HM Complex
Douglas Laboratories Juvenon Pro Cognitive
Integrative Therapeutics K-PAX MitoNutrients
Klean Athlete Klean Antioxidant ™
Klean Athlete Klean Focus®
Thorne L-Arginine Plus Perfusia Plus
Designs For Health Lipoic Acid Supreme
Pure Encapsulations Liver G.I. Detox
Pure Encapsulations LVR Formula
Pure Encapsulations LVR Formula
Metagenics Meta Lipoate® 300 mg
Designs For Health Metabolic Synergy™
Designs For Health Metabolic Synergy™
Metagenics MetaGlycemX™
Metagenics MetaGlycemX
Designs For Health Metal-X-Synergy™
Pure Encapsulations Mitochondria-ATP
Designs For Health Mitochondrial NRG™
Pure Encapsulations NeuroMood Pure Pack
Designs For Health NeuroRenew™
Pure Encapsulations O.N.E.™ Multivitamin
Pure Encapsulations O.N.E.™ Multivitamin
Pure Encapsulations O.N.E.™ Multivitamin
Designs For Health OcuForce™
Pure Encapsulations Polyphenol Nutrients
Pure Encapsulations Polyphenol Nutrients
Pure Encapsulations PureGenomics® UltraMultivitamin
Pure Encapsulations R-Lipoic Acid Stabilized
Pure Encapsulations RevitalAge™ Nerve
Pure Encapsulations RevitalAge™ Ultra
Designs For Health Sensitol™
Designs For Health Stabilized R-Lipoic Acid Supreme
Vitabase Super Antioxidant Formula
Pure Encapsulations Ultra B-Complex with PQQ
Douglas Laboratories Ultra Benfotiamine
Douglas Laboratories Ultra Preventive
Douglas Laboratories Ultra Preventive
Douglas Laboratories Ultra Preventive ®-EZ Swallow
Douglas Laboratories Ultra Preventive One Daily
Douglas Laboratories Ultra Preventive® X
Pure Encapsulations UltraDetox 10-Day Pure Pack
Pure Encapsulations UltraNutrient®
Pure Encapsulations UltraNutrient®
Pure Encapsulations UltraNutrient®
Pure Encapsulations VisionPro Nutrients
Metagenics Wellness Essentials Brain Health Daily Packs
Metagenics Wellness Essentials Healthy Balance Daily Packs
Pure Encapsulations Women's Nutrients
Pure Encapsulations Women's Nutrients