Evidence supporting the use of: Arginine silicate inositol
For the health condition: Body Building
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Arginine silicate inositol (ASI) has been studied to some extent for its potential benefits in body building, primarily due to its role in enhancing nitric oxide (NO) production and improving blood flow. The compound combines arginine (an amino acid and NO precursor), silicate, and inositol, and is marketed to support muscle pumps, vascularity, and exercise performance. There is some scientific evidence from small, short-term studies suggesting that ASI supplementation can increase plasma arginine levels, improve endothelial function, and enhance blood flow, which may theoretically support better nutrient delivery and muscle pump during workouts. For example, a few randomized controlled trials have shown improvements in bench press power and perceived energy in recreationally active men using ASI for 4–12 weeks. However, these effects are generally modest, and the studies often have small sample sizes, lack long-term safety data, and use surrogate markers (like blood flow or NO levels) rather than direct measures of muscle growth or strength gains over time. The evidence does not robustly support dramatic improvements in muscle hypertrophy or strength versus standard arginine or placebo. Thus, while there is some scientific rationale and preliminary data, the overall quality and quantity of the evidence is low (rated 2 out of 5), and more large-scale, long-term studies are needed.
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Other ingredients used for Body Building
7-Keto-DHEAacetyl l-carnitine
adenosine 5-triphosphate disodium (ATP)
alpha-ketoglutarate (AKG)
amino acids
anchovies
ashwagandha
aspartic acid
beta-alanine
bovine
branched-chain amino acids
caffeine
capsaicinoids
coleus forskohlii
conjugated linoleic acid (CLA)
creatine monohydrate
curcumin
gelatin
ginseng
greens blend (proprietary)
hydroxycitric acid
l-isoleucine
iron
l-cysteine
l-glutamine
l-glycine
l-leucine
l-methionine
l-ornithine
l-valine
magnesium
maltodextrin
milk
omega-3 fatty acids
ornithine alpha-ketoglutarate
protein
almond fruit
vitamin D
whey protein
zinc
wheat germ
algae
chickpea protein
brown rice protein
AMP-activated protein kinase (AMPK)
19-NorAndrost-4ene-3b-ol,17-one
17a-di methyl-bol
1,3,7-Trimethylpurine-2,6-dione
2, 17a-dimethyl-17b-hydroxy-5a-androst-2-ene
2a,3a-epithio-17a-methyl-5a-androstan-17b-ol
2, 17a-dimethyl-17b-hydroxy-5a-androstan-1-ene-3-one
2a, 17a-dimethyl-17b-hydroxy-5a-androstan-3-one
4-DHEA
Arginine Alpha Ketoglutarate
Arachidonic Acid
Arginine malate
Alpha glyceryl
Alpha-ketoisocaproic acid
adenosine triphosphate (ATP)
Algal protein
Alpha hydroxyisocaproic acid
Anti-aromatase
Animal protein
Beef Protein
Beef
Beef liver
Bovine Protein
beta-lactoglobulin
Ba Ji Tian
banana
Chia seed
Casein
Cardarine
Citrus
Capsaicin
Capsiate
Chicken
D-Aspartic Acid
Dihydrocapsiate
Deer Velvet
D-Ribose
Dextrose
Egg
Ecdysteroids
Elthyl-Alpha-Guanido-Methyl-Ethanoate
Ecdysterone
Egg protein
glucose
Isoleucine
Milk Protein
yohimbine
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Other health conditions supported by Arginine silicate inositol
Athletic and Exercise AidsBody Building
Energy (lack of)
Exercise
Hypertension