Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Cardarine (also known as GW501516) is a peroxisome proliferator-activated receptor delta (PPARδ) agonist originally developed for metabolic and cardiovascular diseases. In the bodybuilding community, Cardarine is used primarily for its purported ability to enhance endurance, promote fat loss, and improve lipid profiles. There is some preclinical scientific evidence—mainly from animal studies and limited human trials—that GW501516 can increase fatty acid oxidation, elevate exercise endurance, and improve certain aspects of metabolism. However, robust, peer-reviewed human studies focusing specifically on athletes or bodybuilders are lacking.

Notably, Cardarine was discontinued in clinical development due to concerns about cancer risk in animal studies. Furthermore, its use is banned by the World Anti-Doping Agency (WADA) because of its performance-enhancing effects and potential health risks. To date, evidence supporting Cardarine’s use in bodybuilding is limited and comes primarily from mechanistic studies and anecdotal reports rather than large, controlled human clinical trials. Therefore, while there is a scientific rationale for its purported effects, the evidence is not strong or conclusive, and significant safety concerns remain.

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Other ingredients used for Body Building

7-Keto-DHEA
Acetyl L-carnitine
adenosine 5-triphosphate disodium (ATP)
alpha-ketoglutarate (AKG)
amino acids
anchovies
ashwagandha
aspartic acid
beta-alanine
bovine
branched-chain amino acids
caffeine
capsaicinoids
coleus forskohlii
conjugated linoleic acid (CLA)
creatine monohydrate
curcumin
gelatin
ginseng
greens blend (proprietary)
hydroxycitric acid
l-isoleucine
iron
L-cysteine
L-glutamine
L-glycine
L-leucine
L-methionine
L-Ornithine
L-valine
magnesium
maltodextrin
milk
omega-3 fatty acids
ornithine alpha-ketoglutarate
protein
Almond fruit
vitamin D
whey protein
zinc
wheat germ
Algae
chickpea protein
brown rice protein
AMP-activated protein kinase (AMPK)
1,3,7-Trimethylpurine-2,6-dione
2a, 17a-dimethyl-17b-hydroxy-5a-androstan-3-one
4-DHEA
Arginine Alpha Ketoglutarate
Arachidonic Acid
Arginine malate
Alpha glyceryl
Alpha-ketoisocaproic acid
Adenosine triphosphate (ATP)
Algal protein
Alpha hydroxyisocaproic acid
Anti-aromatase
Animal protein
Beef Protein
Beef
Beef liver
Bovine Protein
beta-lactoglobulin
Ba Ji Tian
banana
Chia seed
Casein
Cardarine
Citrus
Capsaicin
Capsiate
Chicken
D-Aspartic Acid
Dihydrocapsiate
Deer Velvet
D-Ribose
Dextrose
Eurycomanone
Egg
Eurycoma Longifolia
Ecdysteroids
Elthyl-Alpha-Guanido-Methyl-Ethanoate
Ecdysterone
Egg protein
Fungus
Fadogia agrestis
Forskolin
glucose
Hydroxymethylbutyrate
HMB Hydroxymethylbutyrate
Isoleucine
Ketosterones
leucine alpha-ketoglutarate
Lactalbumin
Lactoglobulin
Lipids
Marine Protein
Milk Protein
Phytoecdysteroid
Protodioscin
Phosphatidic Acid
Palatinose
Propionate ester
Peptides
Rhaponticum
Synephrine
Safed musli
Ursolic Acid
yohimbine
Zucchini

Other health conditions supported by Cardarine

Athletic and Exercise Aids
Body Building
Cholesterol (high)
Fat Metabolism (poor)
Metabolic Syndrome
Triglycerides (high)
Weight Loss

Products containing Cardarine

We currently have no products on Vitabase that contain this ingredient.