Evidence supporting the use of: L-methionine
For the health condition: Body Building
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
L-methionine is an essential amino acid involved in various metabolic processes, including protein synthesis and methylation reactions. While it is a necessary building block for muscle tissue, the use of L-methionine supplementation specifically for bodybuilding is based on a limited amount of scientific evidence. Most protein-rich diets, commonly followed by bodybuilders, already provide sufficient methionine for physiological needs. Scientific studies have shown that adequate intake of all essential amino acids, including methionine, is required for optimal muscle protein synthesis. However, there is little evidence that supplementing with L-methionine alone, beyond normal dietary levels, directly enhances muscle growth, strength, or recovery in healthy individuals.
Some research suggests that methionine deficiency can impair muscle protein synthesis, but excessive methionine intake does not appear to provide additional anabolic benefits. In fact, high methionine consumption has been linked to potential negative effects, such as increased homocysteine levels, which may elevate cardiovascular risk. Therefore, while L-methionine is scientifically validated as necessary for basic muscle maintenance and growth as part of a complete protein intake, the specific use of L-methionine supplements for bodybuilding lacks robust clinical evidence. Most bodybuilding protocols emphasize overall protein and branched-chain amino acid (BCAA) intake rather than supplementation with individual amino acids like methionine.
Other ingredients used for Body Building
7-Keto-DHEAacetyl l-carnitine
adenosine 5-triphosphate disodium (ATP)
alpha-ketoglutarate (AKG)
amino acids
anchovies
ashwagandha
aspartic acid
beta-alanine
bovine
branched-chain amino acids
caffeine
capsaicinoids
coleus forskohlii
conjugated linoleic acid (CLA)
creatine monohydrate
curcumin
gelatin
ginseng
greens blend (proprietary)
hydroxycitric acid
l-isoleucine
iron
l-cysteine
l-glutamine
l-glycine
l-leucine
l-methionine
l-ornithine
l-valine
magnesium
maltodextrin
milk
omega-3 fatty acids
ornithine alpha-ketoglutarate
protein
almond fruit
vitamin D
whey protein
zinc
wheat germ
algae
chickpea protein
brown rice protein
AMP-activated protein kinase (AMPK)
19-NorAndrost-4ene-3b-ol,17-one
17a-di methyl-bol
1,3,7-Trimethylpurine-2,6-dione
2, 17a-dimethyl-17b-hydroxy-5a-androst-2-ene
2a,3a-epithio-17a-methyl-5a-androstan-17b-ol
2, 17a-dimethyl-17b-hydroxy-5a-androstan-1-ene-3-one
2a, 17a-dimethyl-17b-hydroxy-5a-androstan-3-one
4-DHEA
Arginine Alpha Ketoglutarate
Arachidonic Acid
Arginine malate
Alpha glyceryl
Alpha-ketoisocaproic acid
adenosine triphosphate (ATP)
Algal protein
Alpha hydroxyisocaproic acid
Anti-aromatase
Animal protein
Beef Protein
Beef
Beef liver
Bovine Protein
beta-lactoglobulin
Ba Ji Tian
banana
Chia seed
Casein
Cardarine
Citrus
Capsaicin
Capsiate
Chicken
D-Aspartic Acid
Dihydrocapsiate
Deer Velvet
D-Ribose
Dextrose
Eurycomanone
Egg
Eurycoma Longifolia
Ecdysteroids
Elthyl-Alpha-Guanido-Methyl-Ethanoate
Ecdysterone
Egg protein
Fadogia agrestis
Forskolin
glucose
Isoleucine
Milk Protein
yohimbine
Zucchini
Other health conditions supported by l-methionine
Body BuildingDepression
Fatty Liver Disease
Hair (loss or thinning)
Liver Detoxification
Products containing l-methionine
Designs For Health
Amino Acid Supreme™
Designs For Health
Amino Acid Synergy
Thorne
Amino Complex Berry
Thorne
Amino Complex Lemon
Designs For Health
Amino-D-Tox™
Designs For Health
Amino-D-Tox™
Pure Encapsulations
Amino-NR
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Amino Replete
Metagenics
BioPure Protein® Powder
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Clear Change 10-Day Detox Program with UltraClear Plus Berry
Metagenics
Clear Change 10-Day Detox Program with UltraClear Plus pH
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Clear Change 10-Day Detox Program with UltraClear Plus pH Pineapple Banana
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Clear Change 10-Day Detox Program with UltraClear Plus Pineapple Banana
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Clear Change 10-Day Detox Program with UltraClear Plus Vanilla
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Clear Change 10-Day Detox Program with UltraClear RENEW Berry
Metagenics
Clear Change 10-Day Detox Program with UltraClear RENEW Vanilla
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Clear Change 28-Day Detox Program with UltraClear Plus Berry
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Clear Change 28-Day Detox Program with UltraClear Plus pH Pineapple Banana
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Clear Change 28-Day Detox Program with UltraClear Plus pH Vanilla
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Clear Change 28-Day Detox Program with UltraClear Plus Pineapple Banana
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Clear Change 28-Day Detox Program with UltraClear Plus Vanilla
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Clear Change 28-Day Detox Program with UltraClear RENEW Berry
Metagenics
Clear Change 28-Day Detox Program with UltraClear RENEW Chai
Metagenics
Clear Change 28-Day Detox Program with UltraClear RENEW Vanilla
Integrative Therapeutics
Detoxication Factors
Integrative Therapeutics
Detoxication Factors
Pure Encapsulations
DIM Detox
Pure Encapsulations
Essential Aminos
Douglas Laboratories
Free Form Amino
Metagenics
GI Sustain™ Powder
Vitabase
Hair, Skin & Nails Formula
Pure Encapsulations
HM Complex
Pure Encapsulations
HM Complex
Klean Athlete
Klean Essential Aminos + HMB®
Klean Athlete
Klean Isolate ™
Pure Encapsulations
l-Methionine
Douglas Laboratories
L-Methionine
Metagenics
Lipo-Gen™
Metagenics
Lipo-Gen
Integrative Therapeutics
Lipotropic Complex
Pure Encapsulations
Lipotropic Detox
Pure Encapsulations
Liver G.I. Detox
Designs For Health
LV-GB Complex™
Douglas Laboratories
Muscle Protect™ with HMB®
Designs For Health
PaleoCleanse Plus™
Designs For Health
PaleoCleanse Plus™
Designs For Health
PaleoCleanse Plus™ Detox Program
Designs For Health
PaleoCleanse Plus™Chocolate Detox Kit
Metagenics
Perfect Protein® Pea & Rice Chocolate Powder
Metagenics
Perfect Protein Pea & Rice Vanilla Powder
Metagenics
Perfect Protein Whey Chocolate
Metagenics
Perfect Protein Whey Vanilla
Designs For Health
Plant Protein Cleanse
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Plant Protein Cleanse Plus™ 570g
Vitabase
Super Fat Burner
Metagenics
Ultra Glucose Control® Chocolate
Metagenics
Ultra Glucose Control Chocolate
Metagenics
Ultra Glucose Control Vanilla
Metagenics
Ultra Glucose Control Vanilla
Metagenics
UltraClear Detox Powder
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UltraClear Plus® Detox Powder
Metagenics
UltraClear Plus Detox Powder Berry
Metagenics
UltraClear Plus Detox Powder Pineapple/Banana
Metagenics
UltraClear Plus pH Detox Powder Pineapple/Banana
Metagenics
UltraClear Plus pH Detox Powder Vanilla
Metagenics
UltraClear RENEW Detox Powder Berry
Metagenics
UltraClear RENEW Detox Powder Chai
Metagenics
UltraClear RENEW Detox Powder Vanilla
Pure Encapsulations
UltraDetox 10-Day Pure Pack
Metagenics
UltraGI Replenish® Chocolate
Metagenics
UltraGI Replenish Chocolate
Metagenics
UltraGI Replenish Vanilla
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UltraGI Replenish Vanilla
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UltraInflamX Plus 360°® Chocolate/Orange
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UltraInflamX Plus 360° Mango
Metagenics
UltraInflamX Plus 360° Mango
Metagenics
UltraInflamX Plus 360° Orange
Metagenics
UltraInflamX Plus 360° Original Spice
Metagenics
UltraInflamX Plus 360° Pineapple/Banana
Metagenics
UltraInflamX Plus 360° Pineapple/Banana
Metagenics
UltraMeal Advanced Protein® Dutch Chocolate
Metagenics
UltraMeal Advanced Protein French Vanilla
Metagenics
UltraMeal Advanced Protein Plain
Metagenics
UltraMeal Cardio 360°® Pea/Rice Chocolate
Metagenics
UltraMeal Cardio 360° Pea/Rice Vanilla