Evidence supporting the use of: Iron
For the body system: Brain

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Iron is essential for supporting the brain and nervous system, with robust scientific evidence underpinning its importance. Iron is a key cofactor in the synthesis of neurotransmitters such as dopamine, norepinephrine, and serotonin, which are crucial for mood regulation, attention, and overall cognitive function. Furthermore, iron is indispensable for proper myelination and energy metabolism within neurons. Iron deficiency, particularly during critical periods of brain development (such as infancy, childhood, and pregnancy), has been strongly linked to impaired cognitive, behavioral, and psychomotor development. Numerous studies and reviews, including those published in journals like The Lancet and American Journal of Clinical Nutrition, have demonstrated that iron supplementation in iron-deficient individuals can lead to improvements in attention, memory, and learning outcomes. Even in adults, iron deficiency can result in symptoms such as brain fog, fatigue, and impaired cognitive performance, all of which are reversible with repletion. For these reasons, iron is considered a scientifically validated ingredient to support the brain-body system, especially in populations at risk for deficiency.

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Other ingredients that support Brain

5-Hydroxytryptophan (5-HTP)
acetyl l-carnitine
algal oil
alpha-linolenic acid (ALA)
alpha-pinene
amino acids
anchovies
anthocyanins
apple
ashwagandha
astaxanthin
waterhyssop
basil
bergamot
berry flavor
beta caryophyllene
black cumin
black currant
black garlic
black pepper
sesame
black tea
blackberry
blueberry
Indian frankincense
bovine liver
branched-chain amino acids
broccoli
brussel sprouts
bасора
caffeine
calamari oil
California poppy
cannabis sativa oil
canola oil
cassia bark
catechins
caterpillar mushroom
cauliflower
chaga mushroom
chamomile
cherry
chia seed
Chinese salvia root
chokeberry
choline
cinnamon
citicoline
citrus sinensis (proprietary)
clove
coenzyme Q10 (CoQ10)
coffee fruit
colostrum
copper
Coptis chinensis
cordyceps
cowage seed
creatine monohydrate
turmeric
curcumin
d-alpha tocopherol
damiana
DHA (docosahexaeonic acid)
DHEA (dehydroepiandrosterone)
diallyl disulfide (DADS)
diallyl trisulfide (DATS)
DPA (docosapentaenoic acid)
eleuthero
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fava bean
feverfew
fisetin
fish oil
fish protein
flavonols
folate
fruit and vegetable blend (proprietary)
fruit blend (proprietary)
GABA (gamma aminobutyric acid)
gamma linolenic acid (GLA)
gardenia
garlic bulb
ginger
ginkgo biloba
ginkgo biloba
ginseng
glycerophosphocholine (GPC)
gooseberry
gotu kola
grape
greek mountain tea
green tea
greens blend (proprietary)
guarana
guayusa
hemp oil
hesperetin
hops
huperzine A
Indian tinospora
inositol
iron
knotweed
jujube
kale
kava root
krill oil
kudzu
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
l-carnitine
l-carnosine
l-glycine
l-serine
l-phenylalanine
l-taurine
l-theanine
l-tryptophan
l-tyrosine
lactium casein decapeptide
lavender
lecithin
linoleic acid (LA)
lion's mane
liquid liver fractions
lutein
luteolin
maca
mackerel
magnesium
magnolia
mannitol
marine lipid
matcha
medium chain triglycerides (MCT)
melatonin
moringa
muira puama
n-acetyl-cysteine (NAC)
Acetyl-L-Tyrosine
niacin (vitamin B3)
niacinamide (vitamin B3)
nicotinamide riboside
oat
oleic acid
olive
omega-3 fatty acids
omega-6 fatty acids
omega-9 fatty acids
pantothenic acid (vitamin B5)
passionflower
phenolic acids
phosphatidylcholine
phosphatidylserine
phospholipids
phytocannabinoids
pine bark
polygala root
pomegranate
potassium
pregnenolone
prolyl endopeptidase (PEP)
protein
pumpkin
pyridoxal-5-phosphate (P-5-P)
pyrroloquinoline disodium salt
quercetin
quinoa
reishi mushroom
relora® (proprietary)
resveratrol
rhizome
rhodiola
riboflavin (vitamin B2)
rose oil
rosemary
saffron
sage
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
sardines
sceletium
selenium
shrimp
black ginger
skullcap
soybean
spearmint leaf
specialized pro-resolving mediators (SPMs)
sphaeranthus indicus
spinach
spirulina
strawberry
sulforaphane glucosinolate
thiamin (vitamin B1)
threonic acid
thyme
tocotrienols
tongkat ali
trans-pterostilbene
triphala
almond fruit
ubiquinol
Urolithin A
valerian root
vegetable and fruit blend (proprietary)
velvet bean
vinpocetine
vitamin A
vitamin B
vitamin B12
vitamin B6
vitamin C
vitamin D
vitamin D3
vitamin E
seaweed
water
whey protein
mulberry
zinc
zinc
β-nicotinamide mononucleotide (NMN)
jiaogulan
tangerine
gastrodia
cardamom
mugwort
neem tree
tinospora cordifolia
bee pollen
peony
lingzhi
lingusticum wallichii
sodium salt
kanna
silk tree
chrysanthemum
cistanche
ganoderma
sweet flag
lotus seed
morinda
oriental arborvitae
electrolytes blend (proprietary)
royal jelly
terpene lactones
polyphenols
trace minerals
purslane
St. John's Wort
yerba mate
wheat germ
noni
wood betony
goji berry
hypothalamus
herbal blend (proprietary)
algae
cocoa
AMP-activated protein kinase (AMPK)
ashitaba
DMPX
1,3,7-Trimethylpurine-2,6-dione
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
5-methyltetrahydrofolate glucosamine
7,8-Dihydroxyflavone
7,14-Hydroxy-Docosapentaenoic Acid
Antler
Arginine Creatine
Asiaticoside
Angelica
Arachidonic Acid
Apigenin
Anserine
Anamu
Albizia
Alpha glyceryl
Avocado
Agmatine
Adrafinil
Acetylcholine
Agarwood
Alpha-Lipoic Acid
Astragaloside
Adrenaline
Alpha lactalbumin
anthocyanidins
Asteracea
adenosine triphosphate (ATP)
Acetylsalicylic acid
Algal protein
Aniracetam
anthocyanosides
Apocynin
Arginine silicate
Animal protein
Betony
Black Seed
Beta Phenethylalamine
Bilobalide
Butylphthalide
Baikal Skullcap
Beta-hydroxybutyrate
Biopterin
Blubber oil
Breadnut
Boswellic Acid
Belleric myrobalan
Black galingale
Beef
Beef liver
Bone Marrow
Baccosides
Bacopin
Baicalein
Benfotiamine
Basidiomycota
berry
Brazil nut
Brahmi
Bacopa
Broad Bean
Bee products
Blue-Green Alage
Borage
banana
BCAA
bacoside
Baicalin
Borneol
Bird's nest
Chia seed
Curculigo orchicides
Centrophenoxine
Camellia sinensis
Coconut
Centella triterpenes
Caryophyllene
California chia
Cinnamomum
Crocin
Clary sage
Cocarboxylase
Chinese Mountain Ant
Cyanobacteria
Clerodendrum trichotomum
Carnosine
Catalpol
Cod Liver Oil
Codonopsis
Cactus
Cyanidin
Curcuminoid
Citrus
Catecholamine
Cruciferous
Cytisine
Calea zacatechichi
Centella asiatica
Coca
Chocolate
Creatine
Cinidium
Chicken
Capitate Valerian
Curcuma
Carnosol
Calanus finmarchicus
Catuaba
C-Phycocyanin
Cowslip
Cannabidiol
Calamus
Convolvulus prostratus
Corydalis
Crocetin
Convolvulus Pluricaulis
Celastrus
Cytidine
Crypthecodinium
cola nut
Canscora
Currant
Carnosic acid
Cannabichromene
Cannabigerol
Docosahexaenoic Acid
D-phenylalanine
Dismutase
Danshen
Dendrobium
Dihydromyricetin
Decursin
Dehydroascorbic acid
Deer Velvet
Dibenzo-alpha pyrones
Dihydrolipoic Acid
Dragonhead
Dwarf Morning Glory
Dopamine
Date
Deanol
Dextrose
epicatechin
Egg
Erythrina
Ergothioneine
Elk antler
Emblicanin
Elthyl-Alpha-Guanido-Methyl-Ethanoate
Eicosapentaenoic Acid
Essential Oil Blend
Egg protein
Enokitake
Garlic
glucose
Glycine
jasmine
Ketone Salts
Milk Protein
Mimosa
Phenylethylamine (PEA)
Periwinkle
Poppy
peanut
Pistachio
Quinoa Protein
Rose
Spikenard
Snakeroot (unspecified)
Squid
Sucrose
salt
Sandalwood
Vervain
walnut

Products containing iron

Vitabase Active Man's Formula
Vitabase Active Woman's Multi
Douglas Laboratories Amino-Iron ™
Metagenics Axis Endo™ Mango
Thorne Basic Prenatal Multivitamin
Metagenics Clear Change 10-Day Detox Program with UltraClear Plus Berry
Metagenics Clear Change 10-Day Detox Program with UltraClear Plus pH
Metagenics Clear Change 10-Day Detox Program with UltraClear Plus pH Pineapple Banana
Metagenics Clear Change 10-Day Detox Program with UltraClear Plus Pineapple Banana
Metagenics Clear Change 10-Day Detox Program with UltraClear Plus Vanilla
Metagenics Clear Change 10-Day Detox Program with UltraClear RENEW Berry
Metagenics Clear Change 10-Day Detox Program with UltraClear RENEW Chai
Metagenics Clear Change 10-Day Detox Program with UltraClear RENEW Vanilla
Metagenics Clear Change 28-Day Detox Program with UltraClear Plus Berry
Metagenics Clear Change 28-Day Detox Program with UltraClear Plus pH Pineapple Banana
Metagenics Clear Change 28-Day Detox Program with UltraClear Plus pH Vanilla
Metagenics Clear Change 28-Day Detox Program with UltraClear Plus Pineapple Banana
Metagenics Clear Change 28-Day Detox Program with UltraClear Plus Vanilla
Metagenics Clear Change 28-Day Detox Program with UltraClear RENEW Berry
Metagenics Clear Change 28-Day Detox Program with UltraClear RENEW Chai
Metagenics Clear Change 28-Day Detox Program with UltraClear RENEW Vanilla
Metagenics Collagenics®
Designs For Health DFH Complete Multi™ with Copper & Iron
Vitabase Easy Iron
Metagenics Fem Prenatal®
Thorne Ferrasorb
Designs For Health Ferrochel® Iron Chelate
Metagenics GI Sustain™ Powder
Douglas Laboratories Hair, Skin and Nails Plus
Metagenics Hemagenics
Metagenics Hemagenics
Thorne Iron Bisglycinate NSF
Pure Encapsulations Iron-C
Integrative Therapeutics Iron Complex
Integrative Therapeutics K-PAX MitoNutrients
Metagenics Ketogenic Shake Chocolate
Metagenics Ketogenic Shake Vanilla
Klean Athlete Klean Isolate™ Natural Chocolate Flavor
Klean Athlete Klean Recovery ™
Pure Encapsulations Liquid Iron
Integrative Therapeutics Liquid Iron
Thorne MediClear Plus
Metagenics MetaKids Nutrition Powder Chocolate
Metagenics MetaKids Nutrition Powder Vanilla
Pure Encapsulations Mineral 650
Metagenics Multigenics®
Metagenics Multigenics Chewable Orange
Metagenics Multigenics Intensive Care
Pure Encapsulations Nutrient 950®
Pure Encapsulations Nutrient 950®
Pure Encapsulations Nutrient 950®
Pure Encapsulations OptiFerin-C
Designs For Health Organ Synergy™ 180 Capsules
Designs For Health Organ Synergy™ Powder
Designs For Health PaleoCleanse Plus™
Designs For Health PaleoCleanse Plus™ Detox Program
Designs For Health PaleoCleanse Plus™Chocolate Detox Kit
Designs For Health PaleoGreens®
Designs For Health PaleoGreens®
Designs For Health PaleoMeal®
Metagenics Perfect Protein® Pea & Rice Chocolate Powder
Metagenics Perfect Protein Pea & Rice Vanilla Powder
Metagenics Perfect Protein Whey Chocolate
Integrative Therapeutics Physicians Elemental Diet Dextrose Free
Integrative Therapeutics Physician's Elemental Diet
Integrative Therapeutics Physician's Elemental Diet
Integrative Therapeutics Physicians Elemental Diet Kit
Metagenics PhytoGanix® Tropical Fruit
Metagenics PhytoMulti With Iron
Designs For Health Phytotein™
Designs For Health Plant Protein Cleanse
Designs For Health Plant Protein Cleanse Plus™ 570g
Designs For Health Plant Protein Meal
Designs For Health Plant Protein Meal Plus
Designs For Health Plant Protein Meal
Metagenics PlusOne® Daily Prenatal Packs
Douglas Laboratories Prenatal
Pure Encapsulations PreNatal Nutrients
Pure Encapsulations PreNatal Nutrients
Designs For Health Prenatal Pro™
Pure Encapsulations PureLean® Protein
Pure Encapsulations PurePals with Iron
Designs For Health PurePea™
Douglas Laboratories Timed Release Iron
Metagenics Ultra Calm® Bar Chocolate Coconut
Metagenics Ultra Energy Bar Caramel Sea Salt
Metagenics Ultra Glucose Control® Chocolate
Metagenics Ultra Glucose Control Chocolate
Metagenics Ultra Glucose Control Vanilla
Metagenics Ultra Glucose Control Vanilla
Metagenics Ultra Protein Bar Peanut Butter
Metagenics UltraClear Detox Powder
Metagenics UltraClear Plus® Detox Powder
Metagenics UltraClear Plus Detox Powder Berry
Metagenics UltraClear Plus Detox Powder Pineapple/Banana
Metagenics UltraClear Plus pH Detox Powder Pineapple/Banana
Metagenics UltraClear Plus pH Detox Powder Vanilla
Metagenics UltraClear RENEW Detox Powder Berry
Metagenics UltraClear RENEW Detox Powder Chai
Metagenics UltraClear RENEW Detox Powder Vanilla
Metagenics UltraGI Replenish® Chocolate
Metagenics UltraGI Replenish Chocolate
Metagenics UltraGI Replenish Vanilla
Metagenics UltraGI Replenish Vanilla
Metagenics UltraInflamX Plus 360°® Chocolate/Orange
Metagenics UltraInflamX Plus 360° Mango
Metagenics UltraInflamX Plus 360° Mango
Metagenics UltraInflamX Plus 360° Orange
Metagenics UltraInflamX Plus 360° Original Spice
Metagenics UltraInflamX Plus 360° Pineapple/Banana
Metagenics UltraInflamX Plus 360° Pineapple/Banana
Metagenics UltraMeal Advanced Protein® Dutch Chocolate
Metagenics UltraMeal Advanced Protein French Vanilla
Metagenics UltraMeal Advanced Protein Plain
Metagenics UltraMeal Cardio 360°® Pea/Rice Chocolate
Metagenics UltraMeal Cardio 360° Pea/Rice Vanilla
Metagenics UltraMeal® Daily Support Dutch Chocolate
Metagenics UltraMeal Daily Support Mixed Berry
Metagenics UltraMeal Rice Vanilla
Metagenics Wellness Essentials Women's Daily Packs
Thorne Whey Protein Isolate Chocolate NSF
Designs For Health WheyCool™