Evidence supporting the use of: L-taurine
For the body system: Brain
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
L-taurine is an amino sulfonic acid that plays several important roles in the central nervous system. Scientific research indicates taurine is involved in neuroprotection, osmoregulation, modulation of neurotransmission, and calcium homeostasis. Animal studies and limited human data suggest taurine may help protect neurons from oxidative stress and excitotoxicity, potentially supporting brain health. Taurine is also thought to modulate GABAergic and glycinergic neurotransmission, which may contribute to its calming effects.
Some clinical studies have explored taurine supplementation in neuropsychiatric and neurodegenerative conditions. For example, small studies have examined its use in epilepsy, autism spectrum disorders, and neurodegenerative diseases, though results are preliminary and not always consistent. There is modest evidence from randomized controlled trials that taurine may improve cognitive function and reduce symptoms of fatigue, especially in populations with specific deficiencies or under stress.
Despite these findings, large-scale, high-quality human trials are lacking, and the clinical significance of taurine supplementation for the general population remains uncertain. Most evidence is preclinical or from small pilot studies. Therefore, while scientific mechanisms support taurine’s potential brain-related benefits, more robust research is needed to establish clear recommendations for supplementation in support of the brain-body system.
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alpha-linolenic acid (ALA)
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AMP-activated protein kinase (AMPK)
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