Evidence supporting the use of: Pomegranate
For the body system: Brain
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Pomegranate (Punica granatum) has been traditionally consumed for its health benefits, but more recently, scientific investigations have focused on its effects on brain health. Pomegranate is rich in polyphenols, particularly punicalagins and ellagitannins, which have strong antioxidant and anti-inflammatory properties. Preclinical studies in animal models have indicated that pomegranate extract may help reduce oxidative stress and inflammation in the brain, processes linked to neurodegenerative diseases such as Alzheimer's. Some studies have reported improved memory and learning in rodents given pomegranate juice or extracts.
Human evidence, however, is limited. A few small clinical trials suggest potential cognitive benefits. For example, a 2013 randomized controlled trial published in "Evidence-Based Complementary and Alternative Medicine" found that older adults with mild memory complaints who consumed pomegranate juice daily for four weeks showed improved verbal memory scores and increased functional MRI activity compared to placebo. Despite these promising findings, larger and more rigorous human studies are needed to confirm these effects and to determine optimal dosages.
In summary, while there is emerging scientific evidence—primarily from animal studies and a few small human trials—suggesting pomegranate may support brain health, the strength of evidence is currently modest.
Other ingredients that support Brain
5-Hydroxytryptophan (5-HTP)acetyl l-carnitine
algal oil
alpha-linolenic acid (ALA)
alpha-pinene
amino acids
anchovies
anthocyanins
apple
ashwagandha
astaxanthin
waterhyssop
basil
bergamot
berry flavor
beta caryophyllene
black cumin
black currant
black garlic
black pepper
sesame
black tea
blackberry
blueberry
Indian frankincense
bovine liver
branched-chain amino acids
broccoli
brussel sprouts
bасора
caffeine
calamari oil
California poppy
cannabis sativa oil
canola oil
cassia bark
catechins
caterpillar mushroom
cauliflower
chaga mushroom
chamomile
cherry
chia seed
Chinese salvia root
chokeberry
choline
cinnamon
citicoline
citrus sinensis (proprietary)
clove
coenzyme Q10 (CoQ10)
coffee fruit
colostrum
copper
Coptis chinensis
cordyceps
cowage seed
creatine monohydrate
turmeric
curcumin
d-alpha tocopherol
damiana
DHA (docosahexaeonic acid)
DHEA (dehydroepiandrosterone)
diallyl disulfide (DADS)
diallyl trisulfide (DATS)
DPA (docosapentaenoic acid)
eleuthero
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fava bean
feverfew
fisetin
fish oil
fish protein
flavonols
folate
fruit and vegetable blend (proprietary)
fruit blend (proprietary)
GABA (gamma aminobutyric acid)
gamma linolenic acid (GLA)
gardenia
garlic bulb
ginger
ginkgo biloba
ginkgo biloba
ginseng
glycerophosphocholine (GPC)
gooseberry
gotu kola
grape
greek mountain tea
green tea
greens blend (proprietary)
guarana
guayusa
hemp oil
hesperetin
hops
huperzine A
Indian tinospora
inositol
iron
knotweed
jujube
kale
kava root
krill oil
kudzu
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
l-carnitine
l-carnosine
l-glycine
l-serine
l-phenylalanine
l-taurine
l-theanine
l-tryptophan
l-tyrosine
lactium casein decapeptide
lavender
lecithin
linoleic acid (LA)
lion's mane
liquid liver fractions
lutein
luteolin
maca
mackerel
magnesium
magnolia
mannitol
marine lipid
matcha
medium chain triglycerides (MCT)
melatonin
moringa
muira puama
n-acetyl-cysteine (NAC)
Acetyl-L-Tyrosine
niacin (vitamin B3)
niacinamide (vitamin B3)
nicotinamide riboside
oat
oleic acid
olive
omega-3 fatty acids
omega-6 fatty acids
omega-9 fatty acids
pantothenic acid (vitamin B5)
passionflower
phenolic acids
phosphatidylcholine
phosphatidylserine
phospholipids
phytocannabinoids
pine bark
polygala root
pomegranate
potassium
pregnenolone
prolyl endopeptidase (PEP)
protein
pumpkin
pyridoxal-5-phosphate (P-5-P)
pyrroloquinoline disodium salt
quercetin
quinoa
reishi mushroom
relora® (proprietary)
resveratrol
rhizome
rhodiola
riboflavin (vitamin B2)
rose oil
rosemary
saffron
sage
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
sardines
sceletium
selenium
shrimp
black ginger
skullcap
soybean
spearmint leaf
specialized pro-resolving mediators (SPMs)
sphaeranthus indicus
spinach
spirulina
strawberry
sulforaphane glucosinolate
thiamin (vitamin B1)
threonic acid
thyme
tocotrienols
tongkat ali
trans-pterostilbene
triphala
almond fruit
ubiquinol
Urolithin A
valerian root
vegetable and fruit blend (proprietary)
velvet bean
vinpocetine
vitamin A
vitamin B
vitamin B12
vitamin B6
vitamin C
vitamin D
vitamin D3
vitamin E
seaweed
water
whey protein
mulberry
zinc
zinc
β-nicotinamide mononucleotide (NMN)
jiaogulan
tangerine
gastrodia
cardamom
mugwort
neem tree
tinospora cordifolia
bee pollen
peony
lingzhi
lingusticum wallichii
sodium salt
kanna
silk tree
chrysanthemum
cistanche
ganoderma
sweet flag
lotus seed
morinda
oriental arborvitae
electrolytes blend (proprietary)
royal jelly
terpene lactones
polyphenols
trace minerals
purslane
St. John's Wort
yerba mate
wheat germ
noni
wood betony
goji berry
hypothalamus
herbal blend (proprietary)
algae
cocoa
AMP-activated protein kinase (AMPK)
ashitaba
DMPX
1,3,7-Trimethylpurine-2,6-dione
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
5-methyltetrahydrofolate glucosamine
7,8-Dihydroxyflavone
7,14-Hydroxy-Docosapentaenoic Acid
Antler
Arginine Creatine
Asiaticoside
Angelica
Arachidonic Acid
Apigenin
Anserine
Anamu
Albizia
Alpha glyceryl
Avocado
Agmatine
Adrafinil
Acetylcholine
Agarwood
Alpha-Lipoic Acid
Astragaloside
Adrenaline
Alpha lactalbumin
anthocyanidins
Asteracea
adenosine triphosphate (ATP)
Acetylsalicylic acid
Algal protein
Aniracetam
anthocyanosides
Apocynin
Arginine silicate
Animal protein
Betony
Black Seed
Beta Phenethylalamine
Bilobalide
Butylphthalide
Baikal Skullcap
Beta-hydroxybutyrate
Biopterin
Blubber oil
Breadnut
Boswellic Acid
Belleric myrobalan
Black galingale
Beef
Beef liver
Bone Marrow
Baccosides
Bacopin
Baicalein
Benfotiamine
Basidiomycota
berry
Brazil nut
Brahmi
Bacopa
Broad Bean
Bee products
Blue-Green Alage
Borage
banana
BCAA
bacoside
Baicalin
Borneol
Bird's nest
Chia seed
Curculigo orchicides
Centrophenoxine
Camellia sinensis
Coconut
Centella triterpenes
Caryophyllene
California chia
Cinnamomum
Crocin
Clary sage
Cocarboxylase
Chinese Mountain Ant
Cyanobacteria
Clerodendrum trichotomum
Carnosine
Catalpol
Cod Liver Oil
Codonopsis
Cactus
Cyanidin
Curcuminoid
Citrus
Catecholamine
Cruciferous
Cytisine
Calea zacatechichi
Centella asiatica
Coca
Chocolate
Creatine
Cinidium
Chicken
Capitate Valerian
Curcuma
Carnosol
Calanus finmarchicus
Catuaba
C-Phycocyanin
Cowslip
Cannabidiol
Calamus
Convolvulus prostratus
Corydalis
Crocetin
Convolvulus Pluricaulis
Celastrus
Cytidine
Crypthecodinium
cola nut
Canscora
Currant
Carnosic acid
Cannabichromene
Cannabigerol
Docosahexaenoic Acid
D-phenylalanine
Dismutase
Danshen
Dendrobium
Dihydromyricetin
Decursin
Dehydroascorbic acid
Deer Velvet
Dibenzo-alpha pyrones
Dihydrolipoic Acid
Dragonhead
Dwarf Morning Glory
Dopamine
Date
Deanol
Dextrose
epicatechin
Egg
Erythrina
Ergothioneine
Elk antler
Emblicanin
Elthyl-Alpha-Guanido-Methyl-Ethanoate
Eicosapentaenoic Acid
Essential Oil Blend
Egg protein
Enokitake
Garlic
Glycine
jasmine
Ketone Salts
Milk Protein
Mimosa
Phenylethylamine (PEA)
Periwinkle
Poppy
peanut
Pistachio
Quinoa Protein
Rose
Spikenard
Snakeroot (unspecified)
Squid
Sucrose
salt
Sandalwood
Vervain
walnut
Products containing pomegranate
Pure Encapsulations
Açai 600
Metagenics
AdvaClear
Metagenics
AdvaClear
Pure Encapsulations
Athletic Nutrients
Metagenics
CardioLux® HDL
Metagenics
Clear Change 10-Day Detox Program with UltraClear RENEW Berry
Metagenics
Clear Change 10-Day Detox Program with UltraClear RENEW Vanilla
Metagenics
Clear Change 28-Day Detox Program with UltraClear RENEW Berry
Metagenics
Clear Change 28-Day Detox Program with UltraClear RENEW Chai
Metagenics
Clear Change 28-Day Detox Program with UltraClear RENEW Vanilla
Metagenics
Clear Change Daily Essentials
Designs For Health
H-S-N Radiance™
Thorne
Hormone Advantage DIM Advantage
Vitabase
Life's Essentials Plus
Douglas Laboratories
Methlyated Resveratrol Plus
Thorne
Ovarian Care
Designs For Health
PaleoCleanse Plus™
Designs For Health
PaleoCleanse Plus™
Designs For Health
PaleoCleanse Plus™ Detox Program
Designs For Health
PaleoCleanse Plus™Chocolate Detox Kit
Designs For Health
PaleoReds®
Designs For Health
PhytoBiome™
Metagenics
PhytoMulti™ Multivitamin
Metagenics
PhytoMulti With Iron
Metagenics
PhytoMulti Without Iron
Metagenics
PhytoMultivitamin
Designs For Health
Plant Protein Cleanse Plus™ 570g
Pure Encapsulations
Poly-Prebiotic Powder
Pure Encapsulations
Polyphenol Nutrients
Pure Encapsulations
Polyphenol Nutrients
Pure Encapsulations
Pomegranate Plus
Designs For Health
Prostect™
Pure Encapsulations
PureLean® Protein
Pure Encapsulations
SP Ultimate
Pure Encapsulations
SP Ultimate
Douglas Laboratories
Ultra Preventive
Douglas Laboratories
Ultra Preventive
Douglas Laboratories
Ultra Preventive ®-EZ Swallow
Douglas Laboratories
Ultra Preventive® X
Metagenics
UltraClear RENEW Detox Powder Berry
Metagenics
UltraClear RENEW Detox Powder Chai
Metagenics
UltraClear RENEW Detox Powder Vanilla
Pure Encapsulations
Vascular Relax
Metagenics
Wellness Essentials Active Daily Packs
Metagenics
Wellness Essentials Brain Health Daily Packs
Metagenics
Wellness Essentials® Daily Packs
Metagenics
Wellness Essentials Healthy Balance Daily Packs
Metagenics
Wellness Essentials Men's Vitality Daily Packs
Metagenics
Wellness Essentials Women's Daily Packs
Metagenics
Wellness Essentials Women's Prime Daily Packs
Pure Encapsulations
Women's Nutrients
Pure Encapsulations
XanthiTrim