Evidence supporting the use of: 8-Prenylnaringenin
For the body system: Breasts

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

8-Prenylnaringenin is a potent phytoestrogen found in hops (Humulus lupulus), and it is considered one of the most estrogenic plant-derived compounds. Its use to support the breasts body system—typically in the context of promoting breast health or influencing breast size—is based on its ability to bind to estrogen receptors. Preclinical studies and limited clinical data suggest that 8-prenylnaringenin can mimic estrogenic activity in the body, which theoretically could affect breast tissue, as breast development and maintenance are estrogen-dependent processes.

Some small-scale human studies and in vitro assays have shown that 8-prenylnaringenin can activate estrogen receptors and induce gene expression similar to estradiol. These findings have led to its inclusion in various supplements marketed for female hormonal balance and breast enhancement. However, robust clinical trials specifically examining its efficacy for supporting breast health or augmentation in humans are lacking. Most of the available evidence comes from laboratory or animal studies, with only a few small human studies addressing related endpoints such as menopausal symptoms.

In summary, there is a scientific rationale for 8-prenylnaringenin influencing breast tissue via estrogenic pathways, but direct clinical evidence for its effectiveness in supporting the breasts body system is still limited. As such, the evidence rating is moderate, reflecting preclinical promise and minimal but suggestive human data.

More about 8-Prenylnaringenin
More about Breasts

Other body systems supported by 8-Prenylnaringenin

Breasts
Estrogen
Female Reproductive System
Ovaries
Reproductive System

Products containing 8-Prenylnaringenin

We currently have no products on Vitabase that contain this ingredient.