Evidence supporting the use of: Gamma-linolenic acid
For the body system: Breasts

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Gamma-linolenic acid (GLA) is an omega-6 fatty acid found in plant oils such as evening primrose oil, borage oil, and black currant seed oil. It has been studied for its potential effects on breast health, particularly in the context of cyclical mastalgia (breast pain associated with the menstrual cycle). Several randomized controlled trials and systematic reviews have examined GLA supplementation for this indication. Some studies have shown that GLA can reduce the severity of breast pain, possibly due to its anti-inflammatory properties and its role in modulating prostaglandin synthesis. However, the overall quality of evidence is mixed, with some trials reporting little or no benefit over placebo. The National Institute for Health and Care Excellence (NICE) in the UK acknowledges that GLA may be considered for cyclical mastalgia after other interventions have failed, though it is not a first-line therapy. There is no robust evidence supporting the use of GLA for breast cancer prevention or treatment. In summary, scientific evidence exists, but it is moderate at best and primarily limited to the management of benign breast pain, rather than broader "breast health."

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