Evidence supporting the use of: Progesterone
For the body system: Breasts

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Progesterone is a naturally occurring hormone in the human body and plays a crucial role in the breast body system, particularly in women. Scientifically, progesterone is essential for the development of mammary glands during puberty and pregnancy. During the luteal phase of the menstrual cycle, progesterone works in concert with estrogen to promote the proliferation and differentiation of breast tissue. In pregnancy, high levels of progesterone prepare the breasts for lactation by stimulating the growth of glandular tissue. Clinical uses of progesterone or its analogs include hormone replacement therapy (HRT) and support during fertility treatments, especially to maintain pregnancy in women with luteal phase defects.

Several studies confirm progesterone's role in breast development and function. However, while it is essential for breast tissue growth and function, there is no strong scientific evidence to support the use of supplemental progesterone for enhancing breast size or health in non-deficient, non-pregnant individuals. Furthermore, excessive or inappropriate use may increase the risk of adverse effects, including potential links to breast cancer when combined with estrogen in HRT. In summary, progesterone's use to support the breast system is scientifically justified in specific physiological and therapeutic contexts, particularly relating to reproductive health and pregnancy, but not for general breast enhancement or maintenance.

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