Evidence supporting the use of: Estrogen
For the health condition: Breasts (enhance size)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Estrogen is a steroid hormone that plays a crucial role in the development and maintenance of female secondary sexual characteristics, including breast development. The scientific basis for its use in supporting or enhancing breast size is well-established, particularly in the context of puberty, hormone replacement therapy (HRT), and gender-affirming hormone therapy for transgender women. During puberty, endogenous estrogen promotes the growth of ductal tissue and fat deposition in the breasts, leading to their development. In postmenopausal women or individuals with estrogen deficiency, HRT containing estrogen can help maintain breast tissue, although significant enlargement is less common after initial development is complete.

In transgender women (male-to-female), estrogen therapy is a cornerstone of medical transition and is scientifically validated to induce breast development, though the degree of enlargement varies and may not reach the size typical of cisgender women without surgical augmentation. The use of estrogen purely for cosmetic breast enlargement in cisgender women without hormone deficiency is not standard medical practice due to potential risks (e.g., thromboembolism, cancer risk) and ethical concerns. However, the underlying physiological mechanism—estrogen stimulating breast tissue growth—is incontrovertibly supported by scientific research and clinical experience.

Overall, estrogen’s role in breast development is one of the most well-documented effects of the hormone, justifying a high evidence rating for its use in contexts where breast tissue growth or maintenance is indicated.

More about Estrogen
More about Breasts (enhance size)

Other ingredients used for Breasts (enhance size)

fennel
fenugreek
wild yam
dioscorea
Estrogen
Labisia pumila
Miroestrol
Puerarin

Products containing Estrogen

We currently have no products on Vitabase that contain this ingredient.