Evidence supporting the use of: Vitamin C (ascorbyl palmitate)
For the health condition: Broken Bones

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Ascorbyl palmitate is a fat-soluble form of vitamin C. The use of vitamin C to support bone healing after fractures is supported by some scientific evidence, though the evidence is not robust or conclusive. Vitamin C is essential for collagen synthesis, a key process in bone healing, and deficiency is known to impair fracture repair. Several animal studies have shown that vitamin C supplementation can enhance bone healing and callus formation. A few human studies and clinical trials have also suggested that vitamin C, when used alongside other nutrients, may reduce healing time or improve bone strength post-fracture. However, these studies often use standard ascorbic acid rather than ascorbyl palmitate, and the number of high-quality, randomized controlled trials is limited.

There is no direct evidence that ascorbyl palmitate is superior to other forms of vitamin C for bone healing. The rationale for its use is based on the general importance of vitamin C in collagen synthesis and connective tissue repair. Major guidelines or orthopedic associations do not specifically recommend vitamin C or ascorbyl palmitate supplementation for fracture healing in otherwise healthy individuals. In summary, while there is some scientific rationale and limited clinical evidence for vitamin C’s role in bone repair, the overall evidence supporting ascorbyl palmitate specifically for broken bones is weak.

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