Evidence supporting the use of: 3-acetyl-11-keto-beta-boswellic acid
For the body system: Bronchials
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
3-Acetyl-11-keto-beta-boswellic acid (AKBA) is a bioactive compound derived from the resin of Boswellia serrata, commonly known as frankincense. Historically, extracts of Boswellia have been used in traditional Ayurvedic and Unani medicine for respiratory conditions such as asthma, bronchitis, and cough. The rationale for its use in supporting the bronchial system stems from its anti-inflammatory properties, which were observed in traditional preparations and anecdotal reports. AKBA, one of the principal boswellic acids, has been identified as a potent inhibitor of 5-lipoxygenase, an enzyme involved in the synthesis of leukotrienes that mediate inflammation and bronchoconstriction.
While there are several clinical trials and preclinical studies exploring the effects of Boswellia serrata extracts on inflammatory disorders, direct evidence of AKBA specifically benefiting bronchial health in humans remains limited. Some small clinical studies suggest that Boswellia extracts may help reduce symptoms of asthma and allergic airway inflammation, but these studies often use whole extracts containing multiple boswellic acids, not isolated AKBA. Thus, the evidence is primarily traditional, with limited scientific validation for AKBA alone. Further research is needed to establish the efficacy and safety of AKBA for bronchial support.
More about 3-acetyl-11-keto-beta-boswellic acid
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Other body systems supported by 3-acetyl-11-keto-beta-boswellic acid
BronchialsDigestive System
Gastrointestinal Tract
Intestinal System
Joints
Respiratory System