Pleurisy root (Asclepias tuberosa) has a long history of traditional use in supporting the respiratory system, particularly the bronchial passages. Native American tribes and early European settlers valued pleurisy root as a remedy for respiratory ailments, including pleurisy (inflammation of the lining of the lungs), bronchitis, and other conditions involving cough and congestion. The root was often prepared as a tea or tincture and was thought to help reduce inflammation, promote expectoration, and ease discomfort in the chest.

Despite its extensive historical use, modern scientific research on pleurisy root is limited, and there are very few high-quality clinical studies validating its efficacy for bronchial or respiratory health. Some laboratory studies suggest that pleurisy root contains compounds with mild anti-inflammatory and expectorant properties, but these findings have not been robustly translated into clinical practice. As a result, most claims regarding its benefits for the bronchial system are based on traditional herbal medicine rather than scientific evidence.

In summary, pleurisy root is used to support the bronchial body system primarily due to tradition, with a low level of scientific validation currently available. As with all herbal supplements, individuals should consult a healthcare provider before use, especially given the potential for toxicity at high doses.