Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Zhejiang fritillary (Fritillaria thunbergii), known as "Zhe Bei Mu" in traditional Chinese medicine (TCM), has a long history of use for supporting the bronchial and respiratory system. In TCM, it is primarily used to clear heat and resolve phlegm, particularly in cases of cough with thick sputum, bronchitis, or other lung conditions characterized by phlegm-heat. The bulb of Zhejiang fritillary is included in many classical herbal formulas targeting respiratory symptoms, and its use is documented in centuries-old medical texts.

Modern scientific studies have identified alkaloids such as peimine and peiminine in Fritillaria species, which are believed to exert antitussive (cough-suppressing) and expectorant effects in animal models. Some in vitro and animal research suggests that these constituents may help reduce airway inflammation and mucus production. However, robust clinical trials in humans are lacking, and most existing evidence is based on traditional use and preclinical research rather than high-quality human studies. Therefore, while traditional use is strong and there is some supportive pharmacological evidence, the overall scientific validation is limited. The rating of 3 reflects strong traditional support with partial but incomplete scientific backing.

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