Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Citrus bioflavonoids, often found in supplements alongside vitamin C, have been studied for their potential role in supporting capillary strength and reducing the tendency to bruise. The rationale behind their use stems from their biological activity as antioxidants and their purported ability to stabilize and strengthen blood vessel walls. Historically, flavonoids like rutin and hesperidin have been employed in European phytotherapy to address capillary fragility and related symptoms, including easy bruising.

From a scientific perspective, evidence supporting the use of citrus bioflavonoids for bruise prevention is modest but present. Some clinical studies, often small and sometimes not well-controlled, have shown that combinations of vitamin C with bioflavonoids can reduce capillary permeability and improve symptoms such as bruising and swelling. The mechanism is thought to involve enhancement of collagen synthesis and protection against oxidative damage to blood vessels.

However, rigorous, large-scale randomized controlled trials directly assessing citrus bioflavonoids for the prevention of bruises are lacking. Most evidence is either extrapolated from studies on capillary fragility or is anecdotal. Thus, while there is a plausible biological mechanism and some supportive data, the overall quality and quantity of evidence is limited, justifying a rating of 2. Citrus bioflavonoids may be helpful for some individuals, particularly those with mild capillary fragility, but should not be considered a primary or sole therapy for bruising disorders.

More about citrus bioflavonoids
More about Bruises (prevention)

Other ingredients used for Bruises (prevention)

Other health conditions supported by citrus bioflavonoids

Products containing citrus bioflavonoids

Vitabase Active Woman's Multi
Douglas Laboratories Ascorbplex ® 1000 Buffered
Vitabase Bilberry Extract Plus
Metagenics Bone Builder Active
Douglas Laboratories C-Max ®
Vitabase Chewable Vitamin C
Metagenics Cortico-B5B6®
Metagenics Echinacea Synergy
Designs For Health Electrolyte Synergy™
Douglas Laboratories Hair, Skin and Nails Plus
Vitabase Hair, Skin & Nails Formula
Pure Encapsulations Hair/Skin/Nails Ultra
Metagenics ImmuCore
Metagenics Immune Defense Pack
Integrative Therapeutics K-PAX MitoNutrients
Vitabase Life's Essentials Plus
Douglas Laboratories Malic Acid + Magnesium
Metagenics Multigenics®
Metagenics Multigenics Intensive Care
Metagenics Multigenics Intensive Care without Iron
Metagenics Multigenics without Iron
Douglas Laboratories Natural C
Integrative Therapeutics Nutrivitamin No-Iron
Metagenics PhytoMulti™ Multivitamin
Metagenics PhytoMulti With Iron
Metagenics PhytoMulti Without Iron
Metagenics PhytoMultivitamin
Designs For Health Primal Multi™
Pure Encapsulations PurePals
Pure Encapsulations PurePals with Iron
Vitabase Quercetin Plus
Designs For Health Stellar C™
Metagenics Ultra Potent-C 1000
Metagenics Ultra Potent-C 500
Metagenics Ultra Potent-C Chewable
Metagenics Ultra Potent-C Powder
Douglas Laboratories Ultra Preventive ® Kids Grape Flavor
Douglas Laboratories Ultra Preventive ® Kids Orange Flavor
Thorne Vitamin C With Flavonoids
Integrative Therapeutics Vitamin C with Quercetin
Metagenics Wellness Essentials Active Daily Packs