Evidence supporting the use of: Diclofenac
For the health condition: Bursitis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) with well-established efficacy in the treatment of musculoskeletal inflammatory conditions, including bursitis. Bursitis involves inflammation of a bursa, often resulting in pain, swelling, and reduced mobility. The pathophysiology of bursitis commonly involves local production of prostaglandins and other inflammatory mediators. Diclofenac works by inhibiting cyclooxygenase (COX) enzymes, particularly COX-2, thereby reducing the synthesis of prostaglandins responsible for inflammation and pain.

Numerous randomized controlled trials and meta-analyses support the use of NSAIDs, including diclofenac, for the symptomatic relief of bursitis. Both oral and topical formulations have demonstrated effectiveness in reducing pain and improving function in patients with conditions like subacromial, olecranon, and trochanteric bursitis. Guidelines from rheumatology and orthopedic societies recommend NSAIDs as a first-line pharmacologic therapy for acute bursitis, particularly when non-pharmacological interventions (such as rest and ice) are insufficient.

While diclofenac does not address the underlying cause of bursitis (such as infection or crystal deposition), it is validated for symptom management in non-infectious, non-crystalline bursitis. Adverse effects, especially with systemic administration, must be considered, particularly in patients with gastrointestinal, renal, or cardiovascular risk factors. In summary, the use of diclofenac for bursitis is scientifically justified and supported by high-quality evidence.

More about Diclofenac
More about Bursitis

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