Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin K, particularly in the form of vitamin K2 (menaquinone), has a scientific basis for its use in supporting the regulation of calcium deposition in the body. Vitamin K acts as a cofactor for the activation of matrix Gla protein (MGP), a potent inhibitor of vascular and soft tissue calcification. Without sufficient vitamin K, MGP remains inactive and is unable to prevent inappropriate calcium deposits in blood vessels and soft tissues. Several observational and some interventional studies in humans have found that higher vitamin K status is associated with reduced progression of arterial calcification and improved cardiovascular outcomes. For example, a 2004 study published in "The Journal of Nutrition" found that higher dietary intake of vitamin K2 was linked to reduced arterial calcification and lower risk of coronary heart disease. Interventional studies, such as the 2015 "VitaK-CAC" trial, have shown that vitamin K2 supplementation may slow the progression of vascular calcification in certain populations, although results are not universally consistent and larger randomized controlled trials are needed. Despite these uncertainties, the underlying biochemistry is well-established, and vitamin K deficiency is a recognized risk factor for abnormal calcium metabolism. Therefore, there is moderate scientific validation (rated 3/5) for the use of vitamin K to support proper calcium deposition and to potentially prevent or treat pathological calcium deposits.

More about vitamin K
More about Calcium Deposits

Other ingredients used for Calcium Deposits

Other health conditions supported by vitamin K

Products containing vitamin K

Vitabase Active Woman's Multi
Designs For Health ADK-Evail™
Thorne Advanced Nutrients Multivitamin
Metagenics Axis Endo™ Mango
Thorne Basic Nutrients 2/Day Multivitamin
Thorne Basic Prenatal Multivitamin
Designs For Health BRF 45™
Pure Encapsulations CAL+ with Ipriflavone
Pure Encapsulations CAL+ with Ipriflavone
Pure Encapsulations Calcium K/D
Vitabase Calcium & Magnesium Citrates
Integrative Therapeutics Clinical Nutrients HP
Designs For Health D Evail™ 10K
Designs For Health D-Evail™ Supreme
Designs For Health DFH Complete Multi™
Designs For Health DFH Complete Multi™ with Copper
Designs For Health DFH Complete Multi™ with Copper & Iron
Designs For Health Emulsi-D3 Synergy™
Pure Encapsulations EmulsiSorb K2D3
Metagenics Fem Prenatal®
Douglas Laboratories K2-D3 with Astaxanthin
Vitabase Life's Essentials Plus
Designs For Health Liposomal D Supreme
Douglas Laboratories Liquid D and K
Designs For Health Metabolic Synergy™
Designs For Health Metabolic Synergy™
Metagenics MetaKids Nutrition Powder Chocolate
Metagenics MetaKids Nutrition Powder Vanilla
Thorne Multi-Vitamin Elite NSF
Thorne Multi-Vitamin Elite NSF
Pure Encapsulations Nutrient 950® with Vitamin K
Integrative Therapeutics Nutrivitamin No-Iron
Designs For Health OmegAvail™ Ultra with Vitamin D3, K1 and K2
Designs For Health Osteoben®
Designs For Health OsteoForce™
Designs For Health OsteoForce™
Designs For Health OsteoForce™ Supreme
Integrative Therapeutics Osteoprime Forte
Integrative Therapeutics Osteoprime Ultra
Integrative Therapeutics Physicians Elemental Diet Dextrose Free
Integrative Therapeutics Physician's Elemental Diet
Integrative Therapeutics Physician's Elemental Diet
Integrative Therapeutics Physicians Elemental Diet Kit
Metagenics PhytoMulti™ Multivitamin
Metagenics PhytoMulti With Iron
Metagenics PhytoMulti Without Iron
Metagenics PhytoMultivitamin
Metagenics PlusOne® Daily Prenatal Packs
Douglas Laboratories Prenatal
Pure Encapsulations PreNatal Nutrients
Pure Encapsulations PreNatal Nutrients
Designs For Health Prenatal Pro™
Designs For Health Primal Multi™
Integrative Therapeutics ProThrivers Multivitamin
Pure Encapsulations PureGenomics® Multivitamin
Pure Encapsulations PureGenomics® UltraMultivitamin
Pure Encapsulations PureHeart® K2D
Pure Encapsulations PureLean® Protein
Pure Encapsulations PureResponse™ Multivitamin
Pure Encapsulations Synergy K
Pure Encapsulations Synergy K
Designs For Health Tri-K™
Designs For Health Twice Daily Essential Packets
Designs For Health Twice Daily Multi™
Designs For Health Twice Daily Multi™
Designs For Health Twice Daily Multi™
Douglas Laboratories Ultra Preventive
Douglas Laboratories Ultra Preventive
Douglas Laboratories Ultra Preventive ®-EZ Swallow
Douglas Laboratories ULTRA PREVENTIVE® III W/COPPER
Douglas Laboratories Ultra Preventive® X
Douglas Laboratories Ultra Protein Green
Thorne Vitamin D + K2
Designs For Health Vitamin D Supreme
Designs For Health Vitamin D Supreme
Designs For Health Vitamin D Supreme
Designs For Health Vitamin D Synergy
Metagenics Vitamin D3 10,000 + K
Metagenics Vitamin D3 5000 + K
Thorne Vitamin K (formerly 3-K Complete)
Thorne Vitamin K2
Douglas Laboratories Vitamin K2
Integrative Therapeutics Vitamin K2+D3
Metagenics Wellness Essentials Active Daily Packs
Metagenics Wellness Essentials Brain Health Daily Packs
Metagenics Wellness Essentials® Daily Packs
Metagenics Wellness Essentials Healthy Balance Daily Packs
Metagenics Wellness Essentials Men's Vitality Daily Packs
Metagenics Wellness Essentials Women's Daily Packs
Metagenics Wellness Essentials Women's Prime Daily Packs
Thorne Women's Multi 50+
Pure Encapsulations Women's Nutrients
Pure Encapsulations Women's Nutrients
Designs For Health Women's Twice Daily Essential Packets