Evidence supporting the use of: Baicalin
For the health condition: Cancer Treatment (reducing side effects)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Baicalin is a flavonoid compound extracted from the roots of Scutellaria baicalensis (Chinese skullcap), a herb used in traditional Chinese medicine. Its use as a supportive agent in cancer treatment, specifically for reducing chemotherapy or radiotherapy side effects, has gained attention in recent years due to its anti-inflammatory, anti-oxidant, and cytoprotective properties. Preclinical studies (in vitro and animal models) suggest that baicalin may help protect healthy tissues from damage induced by common cancer therapies. For example, studies have shown baicalin can reduce chemotherapy-induced liver and kidney toxicity and alleviate inflammation caused by radiation. Its mechanisms are thought to involve modulation of oxidative stress and inflammatory pathways (such as inhibition of NF-κB signaling), as well as protection against apoptosis in non-cancerous cells.

However, direct clinical evidence in cancer patients is limited. Most data come from laboratory and animal studies, with only a few early-phase human trials or case reports. While baicalin is recognized in traditional medicine for its broad anti-inflammatory effects, its specific use to mitigate cancer treatment side effects is not yet well established in large-scale clinical practice. Thus, while there is scientific rationale and promising preclinical evidence, robust, high-quality clinical trials are needed to confirm its efficacy and safety for this purpose.

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Products containing Baicalin

We currently have no products on Vitabase that contain this ingredient.