Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Coenzyme Q10 (CoQ10) is a naturally occurring antioxidant that plays a critical role in mitochondrial energy production. Its use in cancer treatment is primarily focused on reducing the side effects of conventional therapies, such as chemotherapy-induced cardiotoxicity, fatigue, and overall oxidative stress. While there is some scientific interest and a modest body of research regarding CoQ10's supportive role, the evidence remains preliminary and limited in quality.

Several small clinical studies and case reports suggest that CoQ10 supplementation may help protect against cardiotoxicity, particularly in patients treated with anthracyclines (e.g., doxorubicin), a class of chemotherapy drugs known to damage heart tissue. Its antioxidant properties may mitigate oxidative damage caused by chemotherapy and radiation, potentially reducing fatigue and improving quality of life. However, large-scale, well-designed randomized controlled trials are lacking, and most studies to date suffer from small sample sizes or methodological limitations.

It is also important to note that there is no solid evidence supporting CoQ10 as an anti-cancer agent itself; rather, its potential benefit lies in side effect management. The National Cancer Institute recognizes ongoing research but does not recommend CoQ10 as a standard adjunct therapy for cancer patients due to insufficient evidence. Thus, while there is scientific rationale and some early data supporting its use for reducing treatment side effects, the current level of evidence is low to moderate (rated 2 out of 5), and further high-quality studies are needed to establish its efficacy and safety in this context.

More about coenzyme Q10 (CoQ10)
More about Cancer Treatment (reducing side effects)

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Other health conditions supported by coenzyme Q10 (CoQ10)

Products containing coenzyme Q10 (CoQ10)

Pure Encapsulations Athletic Nutrients
Douglas Laboratories Citrus-Q10 ™
Douglas Laboratories Co-Enzyme Q10 Softgel
Douglas Laboratories Coenzyme Q-10 with Lipoic Acid
Douglas Laboratories Coenzyme Q-10 with Lipoic Acid
Integrative Therapeutics CoQ10
Integrative Therapeutics COQ10 100 mg Tropical
Pure Encapsulations CoQ10 120 mg
Pure Encapsulations CoQ10 120 mg
Pure Encapsulations CoQ10 120 mg
Integrative Therapeutics COQ10 200 mg Chocolate 30 chew tabs
Pure Encapsulations CoQ10 250 mg
Pure Encapsulations CoQ10 30 mg
Pure Encapsulations CoQ10 500 mg
Pure Encapsulations CoQ10 60 mg
Pure Encapsulations CoQ10 60 mg
Pure Encapsulations CoQ10 60 mg
Pure Encapsulations CoQ10 l-Carnitine Fumarate
Thorne CoQ10 Q-Best 100
Metagenics CoQ10 ST®-100 mg
Metagenics CoQ10 ST-100 mg
Metagenics CoQ10 ST-200 mg
Integrative Therapeutics Detoxication Factors
Integrative Therapeutics Detoxication Factors
Pure Encapsulations Energize Plus™ Pure Pack
Pure Encapsulations Hair/Skin/Nails Ultra
Thorne Heart Health Complex Q-10 Plus
Integrative Therapeutics K-PAX MitoNutrients
Vitabase Life's Essentials Plus
Designs For Health Mito-NR™
Pure Encapsulations Mitochondria-ATP
Designs For Health Mitochondrial NRG™
Pure Encapsulations NeuroMood Pure Pack
Metagenics NutraGems® CoQ10 300
Pure Encapsulations O.N.E.™ Multivitamin
Pure Encapsulations O.N.E.™ Multivitamin
Pure Encapsulations O.N.E.™ Multivitamin
Thorne Omega-3 w/ CoQ10
Thorne Ovarian Care
Integrative Therapeutics ProThrivers Wellness Flav Complex
Pure Encapsulations PureGenomics® UltraMultivitamin
Designs For Health Q-Evail® 100
Designs For Health Q-Evail® 200
Pure Encapsulations Q-Gel® (Hydrosoluble™ CoQ10) 100 mg
Thorne Red Yeast Rice + CoQ10 Choleast
Pure Encapsulations Renual
Pure Encapsulations RevitalAge™ Nerve
Pure Encapsulations RevitalAge™ Ultra
Designs For Health RYR Synergy™
Pure Encapsulations SR-CoQ10 with PQQ
Vitabase Super Fat Burner
Pure Encapsulations Ubiquinol-QH 100 mg
Pure Encapsulations Ubiquinol-QH 200 mg
Pure Encapsulations Ubiquinol VESIsorb®
Integrative Therapeutics UBQH 100 mg
Douglas Laboratories Ultra Preventive 50+ -EZ Swallow
Douglas Laboratories Ultra Preventive One Daily
Pure Encapsulations Ultra Pure Pack
Pure Encapsulations UltraDetox 10-Day Pure Pack
Pure Encapsulations UltraNutrient®
Pure Encapsulations UltraNutrient®
Pure Encapsulations UltraNutrient®
Metagenics Wellness Essentials Brain Health Daily Packs