Evidence supporting the use of: EPA (eicosapentaenoic acid)
For the health condition: Cancer Treatment (reducing side effects)

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Eicosapentaenoic acid (EPA), an omega-3 polyunsaturated fatty acid primarily found in fish oil, has scientific support for its use in managing some side effects associated with cancer treatment, particularly cancer cachexia (a syndrome characterized by weight loss, muscle wasting, and inflammation). Several randomized controlled trials and meta-analyses have investigated the effects of EPA supplementation in patients undergoing chemotherapy or suffering from cancer-induced cachexia. Evidence suggests that EPA may help stabilize or improve body weight and lean body mass, likely due to its anti-inflammatory properties and its ability to modulate metabolic pathways involved in muscle catabolism. Additionally, EPA has been shown in some studies to reduce inflammatory markers and may improve appetite and quality of life in cancer patients. However, results across studies are heterogeneous, with some trials showing significant benefits and others reporting minimal or no effect. The American Society of Clinical Oncology and other professional bodies acknowledge the potential role of EPA-enriched nutritional supplements in selected patients, especially those at risk for or experiencing cachexia, but do not recommend routine use for all cancer patients. Overall, while the evidence base is substantial and growing, it is not definitive, which is why the rating is moderate (3/5). Further large-scale, well-designed clinical trials are needed to clarify the populations most likely to benefit and to refine dosing regimens.

More about EPA (eicosapentaenoic acid)
More about Cancer Treatment (reducing side effects)

Other ingredients used for Cancer Treatment (reducing side effects)

3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
5-methyltetrahydrofolate glucosamine
Acemannan
Acetyl L-carnitine
Agarikon Mushroom
AHCC
Akkermansia muciniphila
Alantolactone
Algae
algal oil
Algal protein
Aloe vera
Alpha Glucans
alpha-ketoglutarate (AKG)
alpha-lipoic acid
amino acids
AMP-activated protein kinase (AMPK)
ampelopsin
anamu
Andrographis
andrographolide
Angelica
anthocyanidins
anti-aromatase
Antrodia camphorata
apigenin
arabinoxylan
Arisaema
Artepillin C
artesunate
ashitaba
ashwagandha
astaxanthin
aster root
astragaloside
astragalus
atractylodes
atractylone
Auricularia
baccosides
bacillus coagulans
bacillus subtilis
bacteria
bael
baicalein
baicalin
Baikal Skullcap
Baphicacanthus cusia
Basidiomycota
basil
BCAA
bee hive
bee products
bee propolis
Beef liver
beet
berberine
berry
beta caryophyllene
beta-glucan
beta-lapachone
betulinic acid
Bidens pilosa
Bifidobacteria
Bifidobacterium
Bifidobacterium adolescentis
Bifidobacterium animalis
Bifidobacterium bifidum
Bifidobacterium breve
Bifidobacterium lactis
Bifidobacterium longum
biota seed
black cumin
black nightshade
black seed
blackberry
blueberry
Boerhavia diffusa
borneol
Boswellia
Boswellic Acid
boxthorne
branched-chain amino acids
Brassica
broccoli
bromelain
buckthorn
bupleurum falcatum
burdock
butein
butyrate triglyceride
C-phycocyanin
caffeic Acid
Calendula
Camellia sinensis
cancerina
cannabidiol
cannabigerol
Cannabis sativa oil
capillary artemisia
capsaicinoids
carnosic acid
carnosol
caryophyllene
cat's claw
catalase
caterpillar mushroom
Celosia
Centella asiatica
chaga mushroom
chamomile
Chinese fleeceflower
Chinese mountain ant
Chinese pond turtle
Chinese salvia root
chirata
chlorella
chlorophyll
chlorophyllin
chokeberry
chrysanthemum
cistanche
Citrus
citrus pectin
Clostridium butyricum
cocoa
coenzyme Q10 (CoQ10)
coix
colostrum
condurango
cordyceps
corilagin
coriolus mushroom
costus
Crinum latifolium
crocetin
Curcuma
curcumen
curcumin
Curcuminoid
cuspidatum root
cyclodextrin
cytokines
d-alpha tocopherol
d-glucarate
daidzein
date
decursin
DHA (docosahexaenoic acid)
diallyl disulfide (DADS)
diallyl sulfide
diallyl trisulfide (DATS)
didymin
DIM (diindolylmethane)
dioscorea
diosgenin
diosmetin
dithiolthiones
DNA
docosahexaenoic Acid
dodder
dong quai root
DPA (docosapentaenoic acid)
Eclipta
eicosapentaenoic acid
eleuthero
enokitake
enzymes blend (proprietary)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
essential oil blend
Eupolyphaga sinensis
evodiamine
fatty acids
ferulic acid
fiber
fiber blend (proprietary)
fibroblast growth factor
fisetin
fish oil
Flammulina velutipes
flat-stem milk-vetch
flavonoids
flavonolignan
flavonols
flavonones
flaxseed
folate
folic acid
folinic acid
Fomitopsis pinicola
fruit
fucoidan
fucosterol
fucoxanthin
fungus
gallic acid
ganoderma
garlic
garlic bulb
genistein
ginger
ginkgetin
ginseng
Ginsenosides
Glucan peptides
Glucoraphanin
Glucosinolates
Glutamine
Glutathione
goji berry
green tea
gum
Gypenoside
Haematococcus pluvialis
Hedyotis
Hematoporphyrin
hemp
hemp oil
Herb Robert
herbal blend (proprietary)
hericium mushroom
hesperetin
hesperidin
HMB hydroxymethylbutyrate
HMR lignan
honey
Honokiol
Huang hua
hydroxymethylbutyrate
hydroxytyrosol
Hyphomycetes
hypsizygus marmoreus
Indian frankincense
Indian sarsparilla
Indian tinospora
indole-3-carbinol
iron
Isatis
Isoalantolactone
isodon excisus
isodon rubescens
isoflavones
isoliquiritigenin
isosilybin
isovitexin
Java brucea
jiaogulan
Job\'s tears
jujube
Kaempferol
kale
Kefir
Kefiran
knotweed
Kokilaksha
l-carnitine
L-cysteine
L-glutamine
L-glutathione
L. lactis
lactiplantibacillus plantarum
Lactobacillus
Lactobacillus acidophilus
Lactobacillus brevis
Lactobacillus casei
Lactobacillus fermentum
Lactobacillus gasseri
Lactobacillus johnsonii
Lactobacillus plantarum
Lactobacillus reuteri
Lactobacillus salivarius
Lactococcus casei
Lactococcus rhamnosus
Lactoferrin
lemongrass
Lentinan
Lentinula edodes mycelia
Ligustrazin
Ligustrum
limonene
lingzhi
lion's mane
lipids
Loranthus
Lycium
lycopene
Maclura tricuspidata
magnesium
magnolol
maitake mushroom
mallow
mangosteen
mangostene xanthone
mangostin
marigold
Marine lipid
Marine protein
Maslinic acid
Mayapple
medium chain triglycerides (MCT)
Melatonin
Mesima
Methylselenocysteine
Milk
Milk Protein
Milk thistle
Mineral ascorbate
Mistletoe
mixed carotenoids
Momordica
Mondo grass
Monoterpenes
Morinda
Moringa
Mushroom
Myrrh
N-acetyl-cysteine (NAC)
Neem tree
Nettle
Niacinamide (vitamin B3)
Nigella seed
Nobiletin
noni
nopal
Oldenlandia diffusa
oleanolic acid
Oligosaccharides
omega-3 fatty acids
Ophiopogon
ornithine alpha-ketoglutarate
Oroxylum indicum
Osthole
Oxymatrine
oyster mushroom
paeoniflorin
Palmitoylethanolamide (PEA)
papaya
Paris polyphylla
parthenolide
Patrinia
pau d'arco
paw paw
Pentacyclic triterpenoids
peony
Pepper
Peptides
perilla
Periwinkle
Petiveria
phenolic compounds
Phenylpropanoids
phlorotannins
phospholipids
Phycocyanin
Phyllanthus
Physalis angulata
phytocannabinoids
Phytoestrogens
phytosterols
Piperine
Plantago
Pleurotus eryngii
plum fruit
Podophyllum
pollen
Polygonatum
polyphenols
polyporous mushroom
Polyporus
polysaccharides
pomegranate
prebiotic blend (proprietary)
probiotics
Propionibacterium freudenreichii
Propolis
protease
protein
proteolytic enzymes
Puerarin
pumpkin
purslane
raspberry
reishi mushroom
resveratrol
Rhabdosia rubescens
rhizome
rosemary
royal jelly
Rubia cordifolia
rutin
S-allylcysteine
Saccharomyces cerevisiae
Salidroside
Salmon Oil
Salvianolic acid
saponins
sarsaparilla
Schisandrins
Schizophyllum commune
scrophularia root
seaweed
selenium
Selenomethionine
Semecarpus anacardium
sesame
Sesamin
Sete sangrias
shiitake mushroom
Shikonin
Shilajit
Shogaol
Sichuan Lovage
siler root
Silybin
smilax
Sophora
soursop
Southern Tsangshu
Soy
soy isoflavones
Soy Protein
specialized pro-resolving mediators (SPMs)
Sphaeranthus indicus
spirulina
Sulfated polysaccharide
Sulforaphane
sulforaphane glucosinolate
suma
Syringic acid
Szechuan lovage
Tanshinone
Tea
Terpenoids
Thistle
Thuja
Thymoquinone
Tinospora cordifolia
tocotrienols
Trametes
Tremella
tributyrin
Trichosanthes
Triphala
Triterpenes
Tumerone
Turkey tail mushroom
turmeric
Turmerones
typhonium
Typhonium flagelliforme
ubiquinol
Uncaria
Urolithin A
Ursolic Acid
vegetable and fruit blend (proprietary)
Vine tea
Viscum coloratum
vitamin A
vitamin B
vitamin B12
vitamin C
vitamin D
vitamin D3
vitamin E
Vitexin
Wax Gourd
wheat grass
Whey protein
Withanolides
Wogonin
Wulinshen
Xanthohumol
Xanthone
Xanthoparmelia
Xanthophyll
Xanthorrhizol
Xylaria nigripes
Yacon
Yellow root
Yew
Yumberry
Zedoary
Zinc
Zingerone
Zingiberene
Zucchini

Products containing EPA (eicosapentaenoic acid)

Thorne Advanced DHA
Vitabase Complete Essential Fatty Acids
Pure Encapsulations DHA Ultimate
Pure Encapsulations DHA Ultimate
Pure Encapsulations EFA Essentials
Pure Encapsulations Energize Plus™ Pure Pack
Pure Encapsulations EPA/DHA
Pure Encapsulations EPA/DHA essentials 1,000 mg
Pure Encapsulations EPA/DHA essentials 1,000 mg
Vitabase EPA / DHA Omega-3
Pure Encapsulations EPA/DHA with Lemon
Pure Encapsulations EPA Ultimate
Klean Athlete Klean Omega ™
Douglas Laboratories Krill Oil
Pure Encapsulations Krill-Plex
Pure Encapsulations Krill-Plex
Metagenics MetaKids DHA
Pure Encapsulations NeuroMood Pure Pack
Pure Encapsulations O.N.E.™ Omega
Pure Encapsulations O.N.E.™ Omega
Thorne Omega-3 w/ CoQ10
Thorne Omega Superb Lemon Berry
Metagenics OmegaGenics Algae EPA-DHA 300 mg
Metagenics OmegaGenics EPA DHA 2400 Fish Oil
Metagenics OmegaGenics EPA-DHA 300 Lemon Lime
Metagenics OmegaGenics Fish Oil
Metagenics OmegaGenics Fish Oil EPA 1200 mg
Metagenics OmegaGenics Fish Oil EPA-DHA 1000 mg
Metagenics OmegaGenics Fish Oil EPA-DHA 1000 mg
Metagenics OmegaGenics Fish Oil EPA-DHA 500 mg
Metagenics OmegaGenics Fish Oil EPA-DHA 500 mg
Metagenics OmegaGenics Fish Oil EPA-DHA 720 mg
Metagenics OmegaGenics Fish Oil EPA-DHA 720 mg
Metagenics OmegaGenics Fish Oil EPA-DHA 720 mg
Metagenics OmegaGenics Fish Oil Mega 10®
Metagenics OmegaGenics Neuro 1000 mg
Designs For Health OmegAvail™ Hi-Po
Designs For Health OmegAvail™ Hi-Po
Designs For Health OmegAvail™ Hi-Po Liquid
Designs For Health OmegAvail™ Liquid
Designs For Health OmegAvail™ Synergy
Designs For Health OmegAvail™ Synergy
Designs For Health OmegAvail™ TG1000
Designs For Health OmegAvail™ Ultra
Designs For Health OmegAvail™ Ultra
Designs For Health OmegAvail™ Ultra DHA
Designs For Health OmegAvail™ Ultra with Vitamin D3, K1 and K2
Douglas Laboratories Opti-EPA 500 ™ Cholesterol Free
Douglas Laboratories Opti-EPA 500 ™ Cholesterol Free
Metagenics PlusOne® Daily Prenatal Packs
Thorne Prenatal DHA
Pure Encapsulations Pro-Resolve Omega
Thorne Pro-Resolving Mediators
Integrative Therapeutics Pure Omega HP
Integrative Therapeutics Pure Omega Liquid
Integrative Therapeutics Pure Omega Ultra HP
Pure Encapsulations PureNutrients EPA/DHA
Douglas Laboratories QÜELL® FISH OIL DHA Ultra SPM
Douglas Laboratories QUELL Fish Oil ® - EPA/DHA Plus D
Metagenics SPM Active
Thorne Super EPA
Thorne Super EPA NSF
Thorne Super EPA Pro
Vitabase Super Omega-3
Pure Encapsulations Ultra Pure Pack
Pure Encapsulations VisionPro EPA/DHA/GLA
Pure Encapsulations VisionPro EPA/DHA/GLA
Metagenics Wellness Essentials Active Daily Packs
Metagenics Wellness Essentials Brain Health Daily Packs
Metagenics Wellness Essentials® Daily Packs
Metagenics Wellness Essentials Healthy Balance Daily Packs
Metagenics Wellness Essentials Men's Vitality Daily Packs
Metagenics Wellness Essentials Women's Daily Packs
Metagenics Wellness Essentials Women's Prime Daily Packs
Designs For Health XanthOmega™ Krill Oil