Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Ginger (Zingiber officinale) is widely used to help manage side effects of cancer treatment, particularly chemotherapy-induced nausea and vomiting (CINV). There is substantial scientific evidence supporting this use. Numerous clinical trials and meta-analyses have demonstrated that ginger, administered as capsules, tea, or extracts, can significantly reduce the severity and frequency of nausea and vomiting in patients undergoing chemotherapy. For example, a systematic review and meta-analysis published in Critical Reviews in Food Science and Nutrition (2019) found that ginger supplementation, especially at doses of 0.5–1.0 grams per day, was effective in reducing acute CINV when used alongside standard antiemetic medications.

The antiemetic effect of ginger is believed to be due to its active constituents, such as gingerols and shogaols, which influence gastrointestinal motility and possess anti-inflammatory and serotonergic (5-HT3 receptor antagonist) properties. While the evidence for ginger's role in reducing other side effects of cancer treatment (such as fatigue or pain) is less robust, its efficacy for CINV is sufficiently supported by randomized controlled trials and is recognized by several oncology guidelines as a complementary therapy.

In summary, the use of ginger to reduce chemotherapy-induced nausea and vomiting is backed by scientific evidence, with a moderate to strong level of support. However, patients should consult their healthcare providers before using ginger, as it may interact with certain medications or be contraindicated in specific situations (e.g., those with bleeding disorders).

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